| Entry |
|
|---|
| Name |
Beraprost sodium (JP18/USAN);
Procylin (TN) |
|---|
| Formula |
C24H29O5. Na
|
|---|
| Exact mass |
420.1913
|
|---|
| Mol weight |
420.4738
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
|
|---|
| Remark |
| Product (DG00160): | D01551<JP> |
|
|---|
| Efficacy |
Antihypertensive, Platelet aggregation inhibitor, Prostaglandin I2 receptor agonist |
|---|
| Comment |
Prostacycline derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
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| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC19 Beraprost
D01551 Beraprost sodium (JP18/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
219 Miscellaneous
2190 Miscellaneous
D01551 Beraprost sodium (JP18/USAN)
3 Agents affecting metabolism
33 Blood and body fluid agents
339 Miscellaneous
3399 Others
D01551 Beraprost sodium (JP18/USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00160 Beraprost
D01551 Beraprost sodium
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
DG00160 Beraprost
D01551 Beraprost sodium
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostacyclin
PTGIR
D01551 Beraprost sodium (JP18/USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01551 Beraprost sodium
D01551 Beraprost sodium
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00160 Beraprost
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
DG00160 Beraprost
|
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| Other DBs |
|
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| KCF data |
ATOM 30
1 C8y C 17.3439 -15.6088
2 C8y C 18.0704 -16.8435
3 C8x C 19.5032 -16.8315
4 C8x C 20.2091 -15.5848
5 C8x C 19.4824 -14.3501
6 C8y C 18.0497 -14.3621
7 C1y C 17.3730 -18.0855
8 C1y C 16.0593 -17.6651
9 C1y C 17.3672 -19.4753
10 O2x O 16.0476 -16.2405
11 C1x C 15.2534 -18.7922
12 C1y C 16.0767 -19.9074
13 C2b C 18.5700 -20.1585
14 O1a O 15.6331 -21.2621
15 C2b C 19.7612 -19.4753
16 C1c C 20.9523 -20.1585
17 C1c C 22.1436 -19.4753
18 O1a O 20.9523 -21.5306
19 C1b C 23.3347 -20.1585
20 C3b C 24.5434 -19.4753
21 C1a C 22.1436 -18.0782
22 C1b C 17.3412 -13.1581
23 C3b C 25.7470 -18.7697
24 C1a C 26.9522 -18.0632
25 C1b C 15.9723 -13.1698
26 C1b C 15.2605 -11.9610
27 C6a C 13.8713 -11.9730
28 O6a O 13.1621 -10.7687 #-
29 O6a O 13.1798 -13.1948
30 Z Na 10.3574 -10.7860 #+
BOND 31
1 7 9 1
2 7 2 1
3 8 10 1
4 8 11 1
5 9 12 1
6 9 13 1
7 12 14 1
8 13 15 2
9 15 16 1
10 16 17 1
11 16 18 1
12 17 19 1
13 19 20 1
14 10 1 1
15 11 12 1
16 5 6 2
17 17 21 1
18 6 1 1
19 6 22 1
20 1 2 2
21 2 3 1
22 3 4 2
23 4 5 1
24 20 23 3
25 7 8 1
26 23 24 1
27 22 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 27 29 2
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