| Entry |
|
|---|
| Name |
Moxisylyte hydrochloride (JAN);
Opilon (TN) |
|---|
| Formula |
C16H25NO3. HCl
|
|---|
| Exact mass |
315.1601
|
|---|
| Mol weight |
315.8355
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Vasodilator (peripheral), alpha1-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C04 PERIPHERAL VASODILATORS
C04A PERIPHERAL VASODILATORS
C04AX Other peripheral vasodilators
C04AX10 Moxisylyte
D01571 Moxisylyte hydrochloride (JAN)
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04B UROLOGICALS
G04BE Drugs used in erectile dysfunction
G04BE06 Moxisylyte
D01571 Moxisylyte hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00287 Moxisylyte
D01571 Moxisylyte hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D01571 Moxisylyte hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00287 Moxisylyte
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8y C 32.0672 -17.4899
2 C8y C 30.8551 -18.1949
3 C8x C 32.0672 -16.0912
4 O2a O 33.2795 -18.1949
5 C8x C 29.6371 -17.4899
6 C1c C 30.8551 -19.5936
7 C8y C 30.8551 -15.3918
8 C1b C 34.4974 -17.4899
9 C8y C 29.6428 -16.0971
10 C1a C 30.8492 -13.9874
11 C1b C 35.7097 -18.1949
12 O7a O 28.4365 -15.3977
13 N1c N 36.9277 -17.4899
14 C7a C 27.2244 -16.0971
15 C1a C 26.0063 -15.3977
16 O6a O 27.2244 -17.4958
17 C1a C 36.9262 -16.0955
18 C1a C 38.1361 -18.1857
19 C1a C 29.6477 -20.2908
20 C1a C 32.0627 -20.2908
21 X Cl 42.3890 -17.8004
BOND 20
1 2 5 1
2 2 6 1
3 3 7 2
4 4 8 1
5 5 9 2
6 7 10 1
7 8 11 1
8 9 12 1
9 11 13 1
10 12 14 1
11 14 15 1
12 14 16 2
13 7 9 1
14 13 17 1
15 13 18 1
16 1 2 2
17 6 19 1
18 1 3 1
19 6 20 1
20 1 4 1
|
|---|
