| Entry |
|
|---|
| Name |
Etilefrine hydrochloride (JP18);
Etilefrine hydrochloride (TN) |
|---|
| Formula |
C10H15NO2. HCl
|
|---|
| Exact mass |
217.087
|
|---|
| Mol weight |
217.6925
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
|
|---|
| Remark |
| Therapeutic category: | 2119 |
| Product (DG00210): | D01573<JP> |
|
|---|
| Efficacy |
Antihypotensive, Cardiotonic, Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA01 Etilefrine
D01573 Etilefrine hydrochloride (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2119 Others
D01573 Etilefrine hydrochloride (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00210 Etilefrine
D01573 Etilefrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D01573 Etilefrine hydrochloride (JP18) <JP>
ADRA2
D01573 Etilefrine hydrochloride (JP18) <JP>
ADRB
D01573 Etilefrine hydrochloride (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01573 Etilefrine hydrochloride
D01573 Etilefrine hydrochloride tablets
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00210 Etilefrine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 14
1 C8y C 27.7200 -15.6100
2 C8x C 27.7200 -17.0100
3 C8x C 28.9100 -17.7100
4 C8x C 30.1000 -17.0100
5 C8y C 30.1000 -15.6100
6 C8x C 28.9100 -14.9100
7 C1c C 31.2900 -14.9100
8 C1b C 32.5500 -15.6100
9 N1b N 33.7400 -14.9100
10 C1b C 34.9300 -15.6100
11 C1a C 36.1900 -14.9100
12 O1a O 31.2900 -13.5100
13 O1a O 26.4600 -14.9100
14 X Cl 34.7900 -17.0800
BOND 13
1 5 7 1
2 7 8 1
3 1 2 2
4 8 9 1
5 2 3 1
6 9 10 1
7 3 4 2
8 10 11 1
9 4 5 1
10 7 12 1
11 5 6 2
12 1 13 1
13 6 1 1
|
|---|
