KEGG   DRUG: Nimetazepam
Entry
D01593                      Drug                                   
Name
Nimetazepam (JAN/INN);
Erimin (TN)
Formula
C16H13N3O3
Exact mass
295.0957
Mol weight
295.2927
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01835  Benzodiazepine sedative-hypnotics
 DG01567  GABA-A receptor agonist
Remark
ATC code: N05CD15
Efficacy
Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
GABR [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Structure map
map07032  Hypnotics
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CD Benzodiazepine derivatives
     N05CD15 Nimetazepam
      D01593  Nimetazepam (JAN/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01835  Benzodiazepine sedative-hypnotics
   D01593  Nimetazepam
  DG01567  GABA-A receptor agonist
   D01593  Nimetazepam
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D01593  Nimetazepam (JAN/INN)
Narcotics and psychotropics in Japan [br08308.html]
 Psychotropics by Cabinet order Article 3 (78 substances)
  D01593
Other DBs
CAS: 2011-67-8
PubChem: 7848656
ChEBI: 31912
LigandBox: D01593
NIKKAJI: J4.431H
KCF data

ATOM        22
            1   C2y C    15.6734  -10.8594
            2   C8y C    14.8313   -9.7498
            3   C8y C    15.1665   -8.3930
            4   N1y N    16.4275   -7.8149
            5   N2x N    17.0792  -10.8846
            6   C5x C    17.6811   -8.4372
            7   C1x C    17.9676   -9.8059
            8   C8x C    14.1594   -7.4246
            9   C8x C    12.8174   -7.8127
            10  C8y C    12.4822   -9.1695
            11  C8x C    13.4893  -10.1376
            12  O5x O    18.7252   -7.5028
            13  N2b N    11.1174   -9.5639 #+
            14  C8y C    15.0389  -12.1091
            15  C8x C    13.6373  -12.1091
            16  C8x C    12.9373  -13.3216
            17  C8x C    13.6373  -14.5340
            18  C8x C    15.0389  -14.5340
            19  C8x C    15.7389  -13.3216
            20  C1a C    16.4492   -6.4400
            21  O3a O    11.1174  -10.9639
            22  O3a O    10.0189   -8.7383 #-
BOND        24
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 2
            22    4  20 1
            23   13  21 2
            24   13  22 1

» Japanese version   » Back

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Drug (3)   
   KEGG DGROUP (2)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (23)   
   KEGG ORTHOLOGY (7)   
   KEGG GENES (16)   
All databases (35)   

Download RDF
DBGET integrated database retrieval system