| Entry |
|
|---|
| Name |
Lormetazepam (JAN/USAN/INN);
Loramet (TN) |
|---|
| Formula |
C16H12Cl2N2O2
|
|---|
| Exact mass |
334.0276
|
|---|
| Mol weight |
335.1847
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG03202 Hypnotic
DG01567 GABA-A receptor agonist
|
|---|
| Remark |
| Therapeutic category: | 1124 |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CD Benzodiazepine derivatives
N05CD06 Lormetazepam
D01657 Lormetazepam (JAN/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D01657 Lormetazepam (JAN/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
D01657 Lormetazepam
DG03202 Hypnotic
D01657 Lormetazepam
DG01567 GABA-A receptor agonist
D01657 Lormetazepam
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03202 Hypnotic
D01657 Lormetazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D01657 Lormetazepam (JAN/USAN/INN) <JP>
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D01657
|
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| Other DBs |
|
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| KCF data |
ATOM 22
1 C2y C 15.6571 -18.0408
2 C8y C 14.8125 -16.9281
3 C8y C 15.1487 -15.5674
4 N1y N 16.4133 -14.9876
5 N2x N 17.0669 -18.0661
6 C5x C 17.6705 -15.6117
7 C1y C 17.9578 -16.9843
8 C8x C 14.1387 -14.5962
9 C8x C 12.7928 -14.9854
10 C8y C 12.4567 -16.3461
11 C8x C 13.4667 -17.3170
12 O1a O 19.2928 -17.4227
13 O5x O 18.7176 -14.6746
14 X Cl 11.1039 -16.7371
15 C8y C 14.9355 -19.2403
16 C8x C 13.5358 -19.2403
17 C8x C 12.8359 -20.4525
18 C8x C 13.5358 -21.6648
19 C8x C 14.9355 -21.6648
20 C8y C 15.6354 -20.4525
21 X Cl 17.0059 -20.4522
22 C1a C 16.3652 -13.5811
BOND 24
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 1
14 6 13 2
15 10 14 1
16 1 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 15 20 2
23 20 21 1
24 4 22 1
|
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