| Entry |
|
|---|
| Name |
Mofezolac (JAN/INN);
Mofezolac (TN) |
|---|
| Formula |
C19H17NO5
|
|---|
| Exact mass |
339.1107
|
|---|
| Mol weight |
339.342
|
|---|
| Structure |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07112 | 1,2-Diphenyl substitution family |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
D01718 Mofezolac
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
D01718 Mofezolac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01718 Mofezolac (JAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01718
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 O2x O 28.2631 -17.3226
2 C8y C 27.4217 -16.2008
3 C8y C 26.1129 -16.6215
4 C8y C 26.1129 -18.0238
5 N5x N 27.4217 -18.4445
6 C8y C 22.4668 -14.5180
7 C8x C 22.4668 -15.9203
8 C8x C 23.6821 -16.6215
9 C8y C 24.8975 -15.9203
10 C8x C 24.8975 -14.5180
11 C8x C 23.6821 -13.8168
12 O2a O 21.2514 -13.8168
13 C1a C 20.0361 -14.5180
14 C8x C 22.4668 -18.7250
15 C8y C 22.4668 -20.1273
16 C8x C 23.6821 -20.8285
17 C8x C 24.8975 -20.1273
18 C8y C 24.8975 -18.7250
19 C8x C 23.6821 -18.0238
20 O2a O 21.2514 -20.8285
21 C1a C 20.0361 -20.1273
22 C1b C 27.8470 -14.8644
23 C6a C 29.2164 -14.5647
24 O6a O 30.1525 -15.5920
25 O6a O 29.6400 -13.2338
BOND 27
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 1 5 1
6 6 7 2
7 7 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 6 11 1
12 9 3 1
13 6 12 1
14 12 13 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 18 4 1
22 15 20 1
23 20 21 1
24 2 22 1
25 22 23 1
26 23 24 2
27 23 25 1
|
|---|
