KEGG   DRUG: Haloxazolam
Entry
D01758                      Drug                                   
Name
Haloxazolam (JP18/INN);
Somelin (TN)
Formula
C17H14BrFN2O2
Exact mass
376.0223
Mol weight
377.2077
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01835  Benzodiazepine sedative-hypnotics
 DG03202  Hypnotic
 DG01567  GABA-A receptor agonist
Remark
Therapeutic category: 1124
Product: D01758<JP>
Efficacy
Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
GABR [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Structure map
map07032  Hypnotics
map07230  GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01758  Haloxazolam (JP18/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01835  Benzodiazepine sedative-hypnotics
   D01758  Haloxazolam
  DG03202  Hypnotic
   D01758  Haloxazolam
  DG01567  GABA-A receptor agonist
   D01758  Haloxazolam
Drug classes [BR:br08332]
 Neuropsychiatric agent
  DG03202  Hypnotic
   D01758  Haloxazolam
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D01758  Haloxazolam (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01758  Haloxazolam
Narcotics and psychotropics in Japan [br08308.html]
 Psychotropics by Cabinet order Article 3 (78 substances)
  D01758
Other DBs
CAS: 59128-97-1
PubChem: 7848821
ChEBI: 31666
LigandBox: D01758
NIKKAJI: J3.200J
KCF data

ATOM        23
            1   C1z C    16.5473  -15.5610
            2   C8y C    15.7133  -14.4620
            3   C8y C    16.0453  -13.1184
            4   N1x N    17.2941  -12.5457
            5   N1y N    17.9395  -15.5166
            6   C5x C    18.5356  -13.1621
            7   C1x C    18.8194  -14.5177
            8   C8x C    15.0478  -12.1593
            9   C8x C    13.7188  -12.5436
            10  C8y C    13.3868  -13.8873
            11  C8x C    14.3842  -14.8461
            12  O5x O    19.5697  -12.2367
            13  X   Br   12.0352  -14.2780
            14  O2x O    16.1592  -16.8988
            15  C1x C    17.3116  -17.6813
            16  C1x C    18.4119  -16.8271
            17  C8y C    14.8624  -16.2537
            18  C8x C    13.6625  -15.5610
            19  C8x C    12.4626  -16.2537
            20  C8x C    12.4626  -17.6393
            21  C8x C    13.6625  -18.3321
            22  C8y C    14.8624  -17.6393
            23  X   F    16.0688  -18.3359
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 1
            18    5  16 1
            19    1  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   20  21 1
            24   21  22 2
            25   17  22 1
            26   22  23 1

» Japanese version   » Back

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (4)   
   KEGG DGROUP (3)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (23)   
   KEGG ORTHOLOGY (7)   
   KEGG GENES (16)   
All databases (39)   

Download RDF
DBGET integrated database retrieval system