| Entry |
|
|---|
| Name |
Tilisolol hydrochloride (JAN);
Selecal (TN) |
|---|
| Formula |
C17H24N2O3. HCl
|
|---|
| Exact mass |
340.1554
|
|---|
| Mol weight |
340.845
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, beta-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01322 Tilisolol
D01795 Tilisolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D01795 Tilisolol hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01322 Tilisolol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C8x C 26.1695 -19.1687
2 C8x C 26.1695 -17.7696
3 C8x C 27.3587 -17.0700
4 C8x C 27.3587 -19.8682
5 C8y C 28.5480 -19.1687
6 C8y C 28.5480 -17.7696
7 C8y C 29.8072 -17.0700
8 C8x C 30.9964 -17.7696
9 N4y N 30.9964 -19.1687
10 C8y C 29.8072 -19.8682
11 O5x O 29.8072 -21.2674
12 O2a O 29.8072 -15.6709
13 C1b C 30.9964 -14.9713
14 C1c C 32.1857 -15.6709
15 C1b C 33.4449 -14.9713
16 N1b N 34.6341 -15.6709
17 C1d C 35.8234 -15.0413
18 O1a O 32.1857 -17.0700
19 C1a C 35.8234 -13.6422
20 C1a C 37.0826 -15.7408
21 C1a C 37.0826 -14.3417
22 C1a C 32.2556 -19.8682
23 X Cl 38.4843 -19.1696
BOND 23
1 4 1 1
2 10 11 2
3 7 12 1
4 12 13 1
5 1 2 2
6 13 14 1
7 2 3 1
8 14 15 1
9 3 6 2
10 15 16 1
11 5 4 2
12 16 17 1
13 5 6 1
14 14 18 1
15 6 7 1
16 17 19 1
17 7 8 2
18 17 20 1
19 8 9 1
20 17 21 1
21 9 10 1
22 9 22 1
23 10 5 1
|
|---|
