| Entry |
|
|---|
| Name |
Clofenamide (JAN/INN) |
|---|
| Formula |
C6H7ClN2O4S2
|
|---|
| Exact mass |
269.9536
|
|---|
| Mol weight |
270.7138
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
DG01534 Carbonic anhydrase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Diuretic, Carbonic anhydrase inhibitor |
|---|
| Comment |
Sulfonamide derivative
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
C03BA Sulfonamides, plain
C03BA07 Clofenamide
D01822 Clofenamide (JAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
D01822 Clofenamide
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
D01822 Clofenamide
DG01534 Carbonic anhydrase inhibitor
D01822 Clofenamide
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D01822 Clofenamide (JAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 15
1 C8y C 8.4700 -16.6600
2 C8x C 8.4700 -18.0600
3 C8x C 9.6824 -18.7600
4 C8y C 10.8949 -18.0600
5 C8y C 10.8949 -16.6600
6 C8x C 9.6824 -15.9600
7 S4a S 7.2576 -15.9600
8 S4a S 12.1260 -15.9490
9 X Cl 12.1260 -18.7710
10 N1a N 6.0451 -15.2600
11 O3c O 7.9730 -14.7435
12 O3c O 6.5537 -17.1569
13 N1a N 13.3384 -15.2490
14 O3c O 11.4267 -14.7381
15 O3c O 12.8268 -17.1626
BOND 15
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 5 8 1
9 4 9 1
10 7 10 1
11 7 11 2
12 7 12 2
13 8 13 1
14 8 14 2
15 8 15 2
|
|---|
