KEGG   DRUG: Icosapent ethyl
Entry
D01892                      Drug                                   
Name
Icosapent ethyl (USAN);
Ethyl icosapentate (JP18);
Epadel S (TN);
Vascepa (TN)
Product
VASCEPA (Amarin Pharma), VASCEPA (Bryant Ranch Prepack)
  Generic
ICOSAPENT (AvKARE), ICOSAPENT (Bryant Ranch Prepack), ICOSAPENT (Dr. Reddy's Laboratories), ICOSAPENT ETHYL (American Health Packaging), ICOSAPENT ETHYL (Amneal Pharmaceuticals LLC), ICOSAPENT ETHYL (Apotex Corp), ICOSAPENT ETHYL (Ascent Pharmaceuticals), ICOSAPENT ETHYL (AvKARE), ICOSAPENT ETHYL (Bryant Ranch Prepack), ICOSAPENT ETHYL (Camber Pharmaceuticals), ICOSAPENT ETHYL (Dr. Reddy's Laboratories), ICOSAPENT ETHYL (EPIC PHARMA), ICOSAPENT ETHYL (Hikma Pharmaceuticals USA), ICOSAPENT ETHYL (Northstar Rx LLC), ICOSAPENT ETHYL (Teva Pharmaceuticals), ICOSAPENT ETHYL (XLCare Pharmaceuticals), ICOSAPENT ETHYL (Zydus Pharmaceuticals USA)
Formula
C22H34O2
Exact mass
330.2559
Mol weight
330.5042
Structure
Simcomp
Class
Hypolipidemic agent
 DG01946  Hypolipidemic agent
Blood modifier agent
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
Remark
Same as: C16184
Therapeutic category: 2189 3399
Product: D01892<JP/US>
Product (mixture): D05255<JP/US>
Efficacy
Antihyperlipidemic, Platelet aggregation inhibitor
  Disease
Hypertriglyceridemia [DS:H01637]
Comment
Treatment of hypertriglyceridemia
Interaction
Structure map
map07052  Antidyslipidemic agents
Brite
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Dyslipidemics, Other
   Icosapent Ethyl
    D01892  Icosapent ethyl (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2189  Others
     D01892  Icosapent ethyl (USAN); Ethyl icosapentate (JP18)
 3  Agents affecting metabolism
  33  Blood and body fluid agents
   339  Miscellaneous
    3399  Others
     D01892  Icosapent ethyl (USAN); Ethyl icosapentate (JP18)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for circulatory system and blood
  25 Other drugs for circulatory system and blood
   D01892  Icosapent ethyl (USAN)
 Other (not belonging to any other category)
  85 Other (not belonging to any other category)
   D01892  Icosapent ethyl (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Ethyl icosapentate
    D01892  Icosapent ethyl (USAN)
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   D01892  Icosapent ethyl
 Blood modifier agent
  DG01950  Antithrombotic agent
   DG01712  Antiplatelet agent
    D01892  Icosapent ethyl
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D01892  Icosapent ethyl
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01892  Ethyl icosapentate
  D01892  Ethyl icosapentate capsules
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D01892
Rx-to-OTC switch list in Japan [br08314.html]
 D01892
Other DBs
CAS: 86227-47-6
PubChem: 7848954
ChEBI: 31570 84883
LigandBox: D01892
NIKKAJI: J391.913G
KCF data

ATOM        24
            1   C1b C     6.3000  -18.8300
            2   O7a O     7.4900  -19.5300
            3   C1a C     5.1100  -19.5300
            4   C7a C     8.6800  -18.8300
            5   C1b C     9.8700  -19.5300
            6   O6a O     8.6800  -17.4300
            7   C1b C    11.0600  -18.8300
            8   C1b C    12.2500  -19.5300
            9   C2b C    13.4400  -18.8300
            10  C2b C    14.8400  -18.8300
            11  C1b C    16.0300  -19.5300
            12  C2b C    17.2200  -18.8300
            13  C2b C    18.6200  -18.8300
            14  C1b C    19.8100  -19.5300
            15  C2b C    21.0000  -18.8300
            16  C2b C    22.4000  -18.8300
            17  C1b C    23.5900  -19.5300
            18  C2b C    24.7800  -18.8300
            19  C2b C    26.1800  -18.8300
            20  C1b C    27.3700  -19.5300
            21  C2b C    28.5600  -18.8300
            22  C2b C    29.9600  -18.8300
            23  C1b C    31.1500  -19.5300
            24  C1a C    32.3400  -18.8300
BOND        23
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     4   5 1
            5     4   6 2
            6     5   7 1
            7     7   8 1
            8     8   9 1
            9     9  10 2
            10   10  11 1
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 1
            15   15  16 2
            16   16  17 1
            17   17  18 1
            18   18  19 2
            19   19  20 1
            20   20  21 1
            21   21  22 2
            22   22  23 1
            23   23  24 1

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