| Entry |
|
|---|
| Name |
Tripamide (JAN/USAN/INN);
Normonal (TN) |
|---|
| Formula |
C16H20ClN3O3S
|
|---|
| Exact mass |
369.0914
|
|---|
| Mol weight |
369.8663
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
|
|---|
| Remark |
| Therapeutic category: | 2149 |
|
|---|
| Efficacy |
Antihypertensive, Na+Cl- symport inhibitor |
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D01895 Tripamide (JAN/USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
D01895 Tripamide
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
D01895 Tripamide
Drug classes [BR:br08332]
Cardiovascular agent
DG02992 Thiazide related diuretic
D01895 Tripamide
DG03231 Antihypertensive
D01895 Tripamide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D01895 Tripamide (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C1x C 15.6800 -16.9400
2 N1y N 16.7300 -16.0300
3 C1x C 16.1000 -14.7000
4 N1b N 17.9200 -16.6600
5 C5a C 19.1100 -15.9600
6 C8y C 20.3700 -16.6600
7 O5a O 19.1100 -14.6300
8 C8x C 21.5600 -15.9600
9 C8x C 20.3700 -18.0600
10 C8y C 22.7500 -16.6600
11 C8x C 21.4900 -18.7600
12 C8y C 22.7500 -18.0600
13 S4a S 23.9400 -16.0300
14 X Cl 23.8700 -18.7600
15 O3c O 23.1000 -14.9100
16 O3c O 24.8500 -17.2900
17 N1a N 25.2000 -15.3300
18 C1y C 14.7700 -14.9100
19 C1y C 14.4900 -16.2400
20 C1y C 13.1600 -16.7300
21 C1x C 12.1100 -15.8200
22 C1x C 12.3900 -14.4900
23 C1y C 13.7200 -14.0000
24 C1x C 12.8800 -15.2600
BOND 27
1 6 9 2
2 8 10 2
3 9 11 1
4 10 12 1
5 10 13 1
6 12 14 1
7 13 15 2
8 13 16 2
9 13 17 1
10 3 18 1
11 11 12 2
12 1 2 1
13 1 19 1
14 2 3 1
15 2 4 1
16 4 5 1
17 18 19 1
18 19 20 1
19 20 21 1
20 21 22 1
21 22 23 1
22 23 18 1
23 5 6 1
24 23 24 1 #Down
25 20 24 1 #Down
26 5 7 2
27 6 8 1
|
|---|
