| Entry |
|
|---|
| Name |
Tranilast (JP18/USAN/INN);
Rizaben (TN) |
|---|
| Formula |
C18H17NO5
|
|---|
| Exact mass |
327.1107
|
|---|
| Mol weight |
327.3313
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01805 Mediator release inhibitor
Dermatological agent
DG03243 Atopic dermatitis agent
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, Antiasthmatic, Mediator release inhibitor |
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D02027 Tranilast (JP18/USAN/INN)
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D02027 Tranilast (JP18/USAN/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for ophthalmologic use
64 Allergy eye drops
D02027 Tranilast (JP18/USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Tranilast
D02027 Tranilast (JP18/USAN/INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01805 Mediator release inhibitor
D02027 Tranilast
Dermatological agent
DG03243 Atopic dermatitis agent
D02027 Tranilast
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
D02027 Tranilast
Drug classes [BR:br08332]
Dermatological agent
DG03243 Atopic dermatitis agent
D02027 Tranilast
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02027 Tranilast
D02027 Tranilast capsules
D02027 Tranilast fine granules
D02027 Tranilast for syrup
D02027 Tranilast ophthalmic solution
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02027
Rx-to-OTC switch list in Japan [br08314.html]
D02027
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C8y C 21.9358 -16.1486
2 C8y C 21.9358 -14.7490
3 N1b N 23.1488 -16.8483
4 C8x C 20.7230 -16.8483
5 C8x C 20.7230 -14.0492
6 C6a C 23.1488 -14.0492
7 C5a C 23.1488 -18.2478
8 C8x C 19.5100 -16.1486
9 C8x C 19.5100 -14.7490
10 O6a O 24.3151 -14.7490
11 O6a O 23.1488 -12.6496
12 C2b C 24.3151 -18.9476
13 O5a O 21.8892 -18.9476
14 C2b C 24.3151 -20.3471
15 C8y C 25.5280 -21.0468
16 C8x C 25.5280 -22.4464
17 C8x C 26.7409 -20.3471
18 C8x C 26.7409 -23.1462
19 C8y C 27.9538 -21.0468
20 C8y C 27.9538 -22.4464
21 O2a O 29.1668 -23.1462
22 C1a C 30.3991 -22.4344
23 O2a O 29.1862 -20.3352
24 C1a C 30.3917 -21.0312
BOND 25
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 6 10 1
10 6 11 2
11 7 12 1
12 7 13 2
13 12 14 2
14 14 15 1
15 15 16 2
16 15 17 1
17 16 18 1
18 17 19 2
19 18 20 2
20 20 21 1
21 8 9 2
22 19 20 1
23 21 22 1
24 19 23 1
25 23 24 1
|
|---|
