| Entry |
|
|---|
| Name |
Ziprasidone mesylate (USAN);
Ziprasidone mesylate hydrate;
Geodon (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H21ClN4OS. CH4SO3. 3H2O
|
|---|
| Exact mass |
562.1323
|
|---|
| Mol weight |
563.0871
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
|
|---|
| Remark |
| Product (DG00892): | D01939<US> D02100<US> |
|
|---|
| Efficacy |
Antipsychotic, Serotonin receptor antagonist, Dopamine D2 receptor antagonist |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AE Indole derivatives
N05AE04 Ziprasidone
D02100 Ziprasidone mesylate (USAN) <US>
USP drug classification [BR:br08302]
Antipsychotics
2nd Generation/Atypical
Ziprasidone
D02100 Ziprasidone mesylate (USAN)
Bipolar Agents
Bipolar Agents, Other
Ziprasidone
D02100 Ziprasidone mesylate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00892 Ziprasidone
D02100 Ziprasidone mesylate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02100 Ziprasidone mesylate (USAN) <US>
Serotonin
HTR2A
D02100 Ziprasidone mesylate (USAN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00892 Ziprasidone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 36
1 N1y N 18.3178 -16.3580
2 C1x C 18.3178 -17.7582
3 C1x C 19.5304 -18.4583
4 N1y N 20.7430 -17.7582
5 C1x C 20.7430 -16.3580
6 C1x C 19.5304 -15.6580
7 C1b C 21.9573 -18.4583
8 C1b C 23.1700 -17.7582
9 C8y C 24.3826 -18.4583
10 C8y C 24.3826 -19.8584
11 C8x C 25.5951 -20.5585
12 C8y C 26.8077 -19.8584
13 C8y C 26.8077 -18.4583
14 C8x C 25.5951 -17.7582
15 N1x N 28.1393 -20.2911
16 C5x C 28.9624 -19.1584
17 C1x C 28.1393 -18.0256
18 C8y C 17.1053 -15.6580
19 N5x N 17.1048 -14.2582
20 S2x S 15.7734 -13.8261
21 C8y C 14.9511 -14.9587
22 C8y C 15.7741 -16.0908
23 C8x C 13.5585 -15.1056
24 C8x C 12.9894 -16.3850
25 C8x C 13.8125 -17.5171
26 C8x C 15.2050 -17.3703
27 O5x O 30.3605 -19.1584
28 X Cl 23.1722 -20.5572
29 S4a S 33.2033 -16.7300
30 O1d O 33.2033 -15.3300
31 O1d O 33.2033 -18.1300
32 O1d O 34.6033 -16.7300
33 C1a C 31.8033 -16.7300
34 O0 O 34.1150 -20.0617
35 O0 O 34.1150 -20.0617
36 O0 O 34.1150 -20.0617
BOND 36
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 9 14 2
16 12 15 1
17 15 16 1
18 16 17 1
19 13 17 1
20 1 18 1
21 18 19 2
22 19 20 1
23 20 21 1
24 21 22 2
25 18 22 1
26 21 23 1
27 23 24 2
28 24 25 1
29 25 26 2
30 22 26 1
31 16 27 2
32 10 28 1
33 29 30 2
34 29 31 2
35 29 32 1
36 29 33 1
BRACKET 1 31.9900 -20.8600 31.9900 -19.3200
1 34.7200 -19.3200 34.7200 -20.8600
1 3
ORIGINAL 1 34
REPEAT 1 35 36
|
|---|
