KEGG   DRUG: Arsenic trioxide
Entry
D02106                      Drug                                   
Name
Arsenic trioxide (JP18/USAN);
Trisenox (TN)
Product
  Generic
Formula
As2O3
Exact mass
197.8279
Mol weight
197.8414
Remark
Same as: C13619
Therapeutic category: 4291
ATC code: L01XX27
Product: D02106<JP/US>
Efficacy
Antineoplastic
  Disease
Acute promyelocytic leukemia [DS:H02542]
Target
PML-RARA [HSA:5371 5914] [KO:K10054 K08527]
  Pathway
hsa05200  Pathways in cancer
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX27 Arsenic trioxide
      D02106  Arsenic trioxide (JP18/USAN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Arsenic Trioxide
    D02106  Arsenic trioxide (JP18/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D02106  Arsenic trioxide (JP18/USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Retinoic acid receptor (RAR)
    PML-RARA
     D02106  Arsenic trioxide (JP18/USAN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02106  Arsenic trioxide
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D02106
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02106
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D02106
Other DBs
CAS: 1327-53-3
PubChem: 7849167
ChEBI: 30621 49900
NIKKAJI: J44.421I

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