 | | DRUG: Clindamycin hydrochloride | |
| Entry |
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| Name |
Clindamycin hydrochloride (JP18/USP);
Cleocin hydrochloride (TN);
Dalacin (TN) |
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| Product |
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| Generic |
CLINDAMYCIN HCL (Advanced Rx Pharmacy of Tennessee), CLINDAMYCIN HCL (Advanced Rx Pharmacy of Tennessee), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (A-S Medication Solutions), CLINDAMYCIN HYDROCHLORIDE (American Health Packaging), CLINDAMYCIN HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), CLINDAMYCIN HYDROCHLORIDE (Asclemed USA), CLINDAMYCIN HYDROCHLORIDE (Asclemed USA), CLINDAMYCIN HYDROCHLORIDE (Aurobindo Pharma Limited), CLINDAMYCIN HYDROCHLORIDE (AvPAK), CLINDAMYCIN HYDROCHLORIDE (Bryant Ranch Prepack), CLINDAMYCIN HYDROCHLORIDE (Bryant Ranch Prepack), CLINDAMYCIN HYDROCHLORIDE (Bryant Ranch Prepack), CLINDAMYCIN HYDROCHLORIDE (Cardinal Health 107), CLINDAMYCIN HYDROCHLORIDE (Chartwell RX), CLINDAMYCIN HYDROCHLORIDE (DIRECT RX), CLINDAMYCIN HYDROCHLORIDE (DIRECT RX), CLINDAMYCIN HYDROCHLORIDE (DIRECT RX), CLINDAMYCIN HYDROCHLORIDE (Denton Pharma), CLINDAMYCIN HYDROCHLORIDE (Denton Pharma), CLINDAMYCIN HYDROCHLORIDE (Direct Rx), CLINDAMYCIN HYDROCHLORIDE (GLENMARK PHARMACEUTICALS), CLINDAMYCIN HYDROCHLORIDE (Golden State Medical Supply), CLINDAMYCIN HYDROCHLORIDE (Greenstone LLC), CLINDAMYCIN HYDROCHLORIDE (Major Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Major Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Micro Labs Limited), CLINDAMYCIN HYDROCHLORIDE (Northwind Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Northwind Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Northwind Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Northwind Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (NuCare Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Pharmasource Meds), CLINDAMYCIN HYDROCHLORIDE (Preferred Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Preferred Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Preferred Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Preferred Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Proficient Rx LP), CLINDAMYCIN HYDROCHLORIDE (Quality Care Products), CLINDAMYCIN HYDROCHLORIDE (REMEDYREPACK), CLINDAMYCIN HYDROCHLORIDE (REMEDYREPACK), CLINDAMYCIN HYDROCHLORIDE (REMEDYREPACK), CLINDAMYCIN HYDROCHLORIDE (REMEDYREPACK), CLINDAMYCIN HYDROCHLORIDE (REMEDYREPACK), CLINDAMYCIN HYDROCHLORIDE (RPK Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (RPK Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (RPK Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (RPK Pharmaceuticals), CLINDAMYCIN HYDROCHLORIDE (Redpharm Drug), CLINDAMYCIN HYDROCHLORIDE (St Mary's Medical Park Pharmacy), CLINDAMYCIN HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLINDAMYCIN HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLINDAMYCIN HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLINDAMYCIN HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLINDAMYCIN HYDROCHLORIDE (Sun Pharmaceutical Industries), CLINDAMYCIN HYDROCHLORIDE (Zydus Lifesciences Limited), CLINDAMYCIN HYDROCHLORIDE (Zydus Pharmaceuticals USA) |
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| Formula |
C18H33ClN2O5S. HCl
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| Exact mass |
460.1565
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| Mol weight |
461.444
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| Structure |
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| Simcomp |
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| Class |
Antibacterial
DG01578 Lincosamide antibiotic
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| Remark |
| Therapeutic category: | 6112 |
| Product (DG00435): | D00277<US> D01073<JP/US> D01990<US> D02132<JP/US> |
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| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
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| Disease |
Infections due to susceptible strains of streptococci [DS: H00333] Infections due to susceptible strains of staphylococci [DS: H01175] |
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| Comment |
Semisynthetic lincosamide
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| Target |
50S ribosomal subunit |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin
D02132 Clindamycin hydrochloride (JP18/USP) <JP/US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA10 Clindamycin
D02132 Clindamycin hydrochloride (JP18/USP) <JP/US>
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FF Lincosamides
J01FF01 Clindamycin
D02132 Clindamycin hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Antibacterials, Other
Clindamycin
D02132 Clindamycin hydrochloride (JP18/USP)
Dermatological Agents
Topical Anti-infectives
Antibacterials, dermatological
Clindamycin
D02132 Clindamycin hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
611 Acting mainly on gram-positive bacteria
6112 Lincomycins
D02132 Clindamycin hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
D02132 Clindamycin hydrochloride
Drug classes [BR:br08332]
Antibacterial
DG01578 Lincosamide antibiotic
D02132 Clindamycin hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
D02132 Clindamycin hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02132 Clindamycin hydrochloride
D02132 Clindamycin hydrochloride capsules
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
DG00435 Clindamycin
Prodrugs [br08324.html]
DG00435
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| Other DBs |
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| KCF data |
ATOM 28
1 C1y C 21.6107 -15.6792
2 C1y C 21.6107 -17.0811
3 C1y C 22.8257 -17.7820
4 C1y C 24.0407 -17.0811
5 C1y C 24.0407 -15.6792
6 O2x O 22.8257 -14.9783
7 S2a S 25.2556 -14.9783
8 C1a C 25.2556 -13.5765
9 O1a O 25.2556 -17.7820
10 O1a O 22.8257 -19.1840
11 O1a O 20.3958 -17.7820
12 C1c C 20.3958 -14.9783
13 N1b N 19.1808 -15.6792
14 C1c C 20.3958 -13.5765
15 X Cl 19.1808 -12.8755
16 C1a C 21.6107 -12.8755
17 C5a C 17.9659 -14.9783
18 C1y C 16.7509 -15.6792
19 O5a O 17.9659 -13.5765
20 N1y N 15.6247 -14.8842
21 C1x C 14.5053 -15.7071
22 C1y C 14.9522 -17.0367
23 C1x C 16.3361 -17.0298
24 C1a C 15.6247 -13.4842
25 C1b C 14.2583 -18.2527
26 C1b C 12.8802 -18.2598
27 C1a C 12.1821 -19.4837
28 X Cl 12.0400 -15.5400
BOND 28
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1 #Down
8 7 8 1
9 4 9 1 #Down
10 3 10 1 #Up
11 2 11 1 #Up
12 1 12 1
13 12 13 1
14 12 14 1
15 14 15 1 #Up
16 14 16 1
17 13 17 1
18 18 17 1 #Down
19 17 19 2
20 18 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 18 23 1
25 20 24 1
26 22 25 1 #Up
27 25 26 1
28 26 27 1
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