| Entry |
|
|---|
| Name |
Echothiophate iodide (USP);
Ecothiopate iodide (JP18/INN);
Phospholine iodide (TN) |
|---|
| Product |
|
|---|
| Formula |
C9H23NO3PS. I
|
|---|
| Exact mass |
383.0181
|
|---|
| Mol weight |
383.2271
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Product (DG01131): | D02193<US> |
|
|---|
| Efficacy |
Miotic, Butyrylcholinesterase inhibitor |
|---|
| Disease |
Open-angle glaucoma [DS: H00612] |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB03 Ecothiopate
D02193 Echothiophate iodide (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01131 Ecothiopate
D02193 Echothiophate iodide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01131 Ecothiopate
D02193 Echothiophate iodide
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D02193 Echothiophate iodide
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D02193 Echothiophate iodide (USP) <US>
BCHE
D02193 Echothiophate iodide (USP) <US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02193 Ecothiopate iodide
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01131 Ecothiopate
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01131 Ecothiopate
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 O2b O 27.0988 -16.1378
2 P1b P 28.3142 -15.4367
3 S2a S 29.5294 -16.1378
4 C1b C 30.6980 -15.4367
5 C1b C 31.9132 -16.1378
6 N1d N 33.1286 -15.4367 #+
7 C1a C 34.3438 -16.1378
8 O3b O 27.0521 -14.7355
9 C1b C 27.0988 -17.5400
10 C1a C 25.8836 -18.2412
11 O2b O 29.4826 -14.7355
12 C1b C 29.4827 -13.3333
13 C1a C 30.6980 -12.6322
14 C1a C 33.1286 -14.0344
15 C1a C 34.5538 -14.7355
16 X I 33.1567 -17.5000 #-
BOND 14
1 2 8 2
2 3 4 1
3 1 9 1
4 1 2 1
5 9 10 1
6 4 5 1
7 2 11 1
8 11 12 1
9 5 6 1
10 12 13 1
11 2 3 1
12 6 14 1
13 6 7 1
14 6 15 1
|
|---|
