| Entry |
|
|---|
| Name |
Foscarnet sodium hydrate (JAN);
Foscarnet sodium hexahydrate;
Trisodium phosphonoformate hexahydrate;
Foscavir (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
CO5P. 6H2O. 3Na
|
|---|
| Exact mass |
299.981
|
|---|
| Mol weight |
300.0424
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01937 Anti-cytomegalovirus agent
|
|---|
| Remark |
| Therapeutic category: | 6250 |
| Product (DG00651): | D02267<JP/US> |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Comment |
Phosphonic acid derivative
|
|---|
| Target |
HCMV DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AD Phosphonic acid derivatives
J05AD01 Foscarnet
D02267 Foscarnet sodium hydrate (JAN) <JP/US>
USP drug classification [BR:br08302]
Antivirals
Anti-cytomegalovirus (CMV) Agents
Foscarnet
D02267 Foscarnet sodium hydrate (JAN)
Antiherpetic Agents
Foscarnet
D02267 Foscarnet sodium hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D02267 Foscarnet sodium hydrate (JAN)
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00651 Foscarnet
D02267 Foscarnet sodium hydrate
Drug classes [BR:br08332]
Antiviral
DG01937 Anti-cytomegalovirus agent
D02267 Foscarnet sodium hydrate
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D02267 Foscarnet sodium hydrate (JAN) <JP/US>
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00651 Foscarnet
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00651 Foscarnet
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 O0 O 35.4900 -21.2800
2 Z Na 26.7400 -23.1000 #+
3 Z Na 31.0100 -21.8400 #+
4 Z Na 24.1500 -20.5800 #+
5 P1b P 27.3700 -20.5800
6 C6a C 28.7700 -20.5800
7 O1c O 27.3700 -21.9800 #-
8 O1c O 25.9700 -20.5800 #-
9 O1c O 27.3700 -19.1800
10 O6a O 29.4700 -21.8400 #-
11 O6a O 29.4700 -19.3900
12 O0 O 35.4900 -21.2800
13 O0 O 35.4900 -21.2800
14 O0 O 35.4900 -21.2800
15 O0 O 35.4900 -21.2800
16 O0 O 35.4900 -21.2800
BOND 6
1 5 7 1
2 5 8 1
3 5 9 2
4 6 10 1
5 5 6 1
6 6 11 2
BRACKET 1 33.4600 -22.1200 33.4600 -20.4400
1 35.9800 -20.4400 35.9800 -22.1200
1 6
ORIGINAL 1 1
REPEAT 1 12 13 14 15 16
|
|---|
