| Entry |
|
|---|
| Name |
Benzylpenicillin (INN);
Penicillin G |
|---|
| Formula |
C16H18N2O4S
|
|---|
| Exact mass |
334.0987
|
|---|
| Mol weight |
334.3901
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Penicillium chrysogenum [TAX: 5076]
|
|---|
| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG01778 beta-Lactamase sensitive penicillin
Transporter substrate
DG02860 SLC22A8 substrate
|
|---|
| Remark |
| Product (DG00534): | D01053<JP/US> D02157<JP/US> D05408<US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Metabolism |
Transporter: SLC22A8 [HSA: 9376]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
J01CE Beta-lactamase sensitive penicillins
J01CE01 Benzylpenicillin
D02336 Benzylpenicillin (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA14 Benzylpenicillin
D02336 Benzylpenicillin (INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00534 Benzylpenicillin
D02336 Benzylpenicillin
DG01778 beta-Lactamase sensitive penicillin
DG00534 Benzylpenicillin
D02336 Benzylpenicillin
Transporter substrate
DG02860 SLC22A8 substrate
D02336 Benzylpenicillin
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase sensitive penicillin
D02336 Benzylpenicillin (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D02336
Prodrugs [br08324.html]
D02336
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00534 Benzylpenicillin
DG01778 beta-Lactamase sensitive penicillin
DG00534 Benzylpenicillin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase sensitive penicillin
DG00534 Benzylpenicillin
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C1y C 15.5849 -20.3259
2 C5x C 15.5849 -21.7303
3 N1y N 16.9893 -21.7303
4 C1y C 16.9893 -20.3259
5 C1y C 18.3234 -22.1515
6 C1z C 19.1659 -21.0280
7 S2x S 18.3234 -19.9045
8 C1a C 20.1491 -22.0111
9 C1a C 20.1491 -20.0449
10 C6a C 18.8149 -23.4856
11 O6a O 20.2192 -23.4856
12 O6a O 17.9722 -24.6090
13 N1b N 14.3912 -19.6237
14 C5a C 13.1975 -20.3259
15 O5x O 14.3912 -22.4324
16 O5a O 13.1975 -21.7303
17 C1b C 11.9784 -19.6286
18 C8y C 10.7864 -20.3236
19 C8x C 9.5732 -19.6232
20 C8x C 8.3601 -20.3236
21 C8x C 8.3601 -21.7244
22 C8x C 9.5732 -22.4248
23 C8x C 10.7864 -21.7244
BOND 25
1 1 2 1
2 2 3 1
3 3 4 1
4 1 4 1
5 3 5 1
6 5 6 1
7 6 7 1
8 4 7 1
9 6 8 1
10 6 9 1
11 5 10 1 #Down
12 10 11 1
13 10 12 2
14 1 13 1 #Up
15 13 14 1
16 2 15 2
17 14 16 2
18 14 17 1
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
|
|---|
