| Entry |
|
|---|
| Name |
Bisoprolol (JAN/USAN/INN) |
|---|
| Formula |
C18H31NO4
|
|---|
| Exact mass |
325.2253
|
|---|
| Mol weight |
325.443
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG03231 Antihypertensive
|
|---|
| Remark |
| Therapeutic category: | 2149 |
| Product (DG00316): | D02342<JP> D00634<JP/US> |
|
|---|
| Efficacy |
Antihypertensive, beta1-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07214 | beta-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AB Beta blocking agents, selective
C07AB07 Bisoprolol
D02342 Bisoprolol (JAN/USAN/INN) <JP>
USP drug classification [BR:br08302]
Cardiovascular Agents
Beta-adrenergic Blocking Agents
Beta-1 Selective
Bisoprolol
D02342 Bisoprolol (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D02342 Bisoprolol (JAN/USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00316 Bisoprolol
D02342 Bisoprolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00316 Bisoprolol
D02342 Bisoprolol
DG03231 Antihypertensive
DG00316 Bisoprolol
D02342 Bisoprolol
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D02342 Bisoprolol
DG01653 Antiarrhythmics
D02342 Bisoprolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D02342 Bisoprolol (JAN/USAN/INN) <JP>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D02342
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00316 Bisoprolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00316 Bisoprolol
DG03231 Antihypertensive
DG00316 Bisoprolol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C8y C 22.1200 -14.8400
2 C8x C 23.3800 -15.5400
3 C8x C 20.9300 -15.5400
4 O2a O 22.1200 -13.4400
5 C8x C 23.3800 -16.9400
6 C8x C 20.9300 -16.9400
7 C1b C 23.3100 -12.7400
8 C8y C 22.1200 -17.6400
9 C1c C 24.5700 -13.4400
10 C1b C 22.1200 -19.0400
11 C1b C 25.7600 -12.7400
12 O1a O 24.5700 -14.8400
13 O2a O 20.9300 -19.7400
14 N1b N 26.9500 -13.4400
15 C1b C 19.7400 -18.9700
16 C1c C 28.2100 -12.7400
17 C1b C 18.4800 -19.7400
18 C1a C 29.4000 -13.4400
19 C1a C 28.2100 -11.2700
20 O2a O 17.2900 -18.9700
21 C1c C 16.1000 -19.6700
22 C1a C 14.8400 -18.9700
23 C1a C 16.1000 -21.1400
BOND 23
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 5 8 1
8 7 9 1
9 8 10 1
10 9 11 1
11 9 12 1
12 10 13 1
13 11 14 1
14 13 15 1
15 14 16 1
16 15 17 1
17 16 18 1
18 16 19 1
19 17 20 1
20 20 21 1
21 21 22 1
22 21 23 1
23 6 8 2
|
|---|
