| Entry |
|
|---|
| Name |
Lincomycin hydrochloride hydrate (JP18/USP);
LCM;
Lincocin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C18H34N2O6S. HCl. H2O
|
|---|
| Exact mass |
460.201
|
|---|
| Mol weight |
461.0136
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01578 Lincosamide antibiotic
|
|---|
| Remark |
| Therapeutic category: | 6112 |
| Product (DG00607): | D02346<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FF Lincosamides
J01FF02 Lincomycin
D02346 Lincomycin hydrochloride hydrate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Antibacterials, Other
Lincomycin
D02346 Lincomycin hydrochloride hydrate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
611 Acting mainly on gram-positive bacteria
6112 Lincomycins
D02346 Lincomycin hydrochloride hydrate (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00607 Lincomycin
D02346 Lincomycin hydrochloride hydrate
Drug classes [BR:br08332]
Antibacterial
DG01578 Lincosamide antibiotic
D02346 Lincomycin hydrochloride hydrate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
D02346 Lincomycin hydrochloride hydrate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02346 Lincomycin hydrochloride hydrate
D02346 Lincomycin hydrochloride injection
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00607 Lincomycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
DG00607 Lincomycin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 X Cl 42.2026 -19.1151
2 O0 O 45.2623 -19.1151
3 C1y C 33.7529 -17.8570
4 C1c C 32.5531 -17.1614
5 O2x O 34.9700 -17.1614
6 C1y C 33.7529 -19.2480
7 N1b N 31.3475 -17.8570
8 C1c C 32.5415 -15.4923
9 C1y C 36.1698 -17.8570
10 C1y C 34.9700 -19.9436
11 O1a O 32.5531 -19.9493
12 C5a C 30.1363 -17.1673
13 C1a C 33.7356 -14.7851
14 O1a O 31.3300 -14.8026
15 C1y C 36.1698 -19.2480
16 S2a S 37.3813 -17.1614
17 O1a O 34.9700 -21.3463
18 C1y C 28.9248 -17.8570
19 O5a O 30.1363 -15.7762
20 O1a O 37.3813 -19.9436
21 C1a C 38.5869 -17.8570
22 C1x C 29.3537 -19.1728
23 N1y N 27.5453 -17.8570
24 C1y C 28.2349 -19.9841
25 C1x C 27.1222 -19.1728
26 C1a C 26.7280 -16.7383
27 C1b C 28.2349 -21.3695
28 C1b C 27.0295 -22.0535
29 C1a C 25.8239 -21.3579
BOND 28
1 3 4 1
2 3 5 1
3 3 6 1
4 4 7 1 #Down
5 4 8 1
6 5 9 1
7 6 10 1
8 6 11 1 #Up
9 7 12 1
10 8 13 1
11 8 14 1 #Down
12 9 15 1
13 9 16 1 #Down
14 10 17 1 #Up
15 18 12 1 #Down
16 12 19 2
17 15 20 1 #Down
18 16 21 1
19 18 22 1
20 18 23 1
21 22 24 1
22 23 25 1
23 23 26 1
24 24 27 1 #Up
25 27 28 1
26 28 29 1
27 10 15 1
28 24 25 1
|
|---|
