| Entry |
|
|---|
| Name |
Dipivefrin (USAN);
Dipivefrine (INN) |
|---|
| Formula |
C19H29NO5
|
|---|
| Exact mass |
351.2046
|
|---|
| Mol weight |
351.4373
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, Adrenergic receptor agonist |
|---|
| Comment |
Active form of prodrug: Adrenaline (Epinephrine) [DR: D00095]
Catecholamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA02 Dipivefrine
D02349 Dipivefrin (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01129 Dipivefrine
D02349 Dipivefrin
DG01951 Catecholamine adrenergic receptor agonist
DG01129 Dipivefrine
D02349 Dipivefrin
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01129 Dipivefrine
D02349 Dipivefrin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D02349 Dipivefrin (USAN)
ADRA2
D02349 Dipivefrin (USAN)
ADRB
D02349 Dipivefrin (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01129 Dipivefrine
DG01951 Catecholamine adrenergic receptor agonist
DG01129 Dipivefrine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01129 Dipivefrine
Prodrugs [br08324.html]
DG01129
|
|---|
| Other DBs |
|
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| KCF data |
ATOM 25
1 C8y C 10.7100 -23.0300
2 C8y C 10.7100 -24.4300
3 C8x C 11.9000 -22.3300
4 O7a O 9.5200 -22.3300
5 C8x C 11.9700 -25.0600
6 O7a O 9.5900 -25.0600
7 C8y C 13.1600 -22.9600
8 C7a C 9.5200 -21.0000
9 C8x C 13.1600 -24.3600
10 C1c C 14.3500 -22.2600
11 C1d C 8.2600 -20.3000
12 O6a O 10.7100 -20.2300
13 C1b C 15.5400 -22.8900
14 O1a O 14.3500 -20.8600
15 N1b N 16.7394 -22.1679
16 C1a C 17.9665 -22.8466
17 C7a C 9.5900 -26.4600
18 C1d C 8.3776 -27.1600
19 O6a O 10.8024 -27.1600
20 C1a C 7.1821 -26.4696
21 C1a C 8.3775 -28.5598
22 C1a C 7.1820 -27.8503
23 C1a C 7.0593 -21.0199
24 C1a C 8.2369 -18.9002
25 C1a C 7.0362 -19.6201
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 7 10 1
10 8 11 1
11 8 12 2
12 10 13 1
13 10 14 1
14 7 9 2
15 13 15 1
16 15 16 1
17 6 17 1
18 17 18 1
19 17 19 2
20 18 20 1
21 18 21 1
22 18 22 1
23 11 23 1
24 11 24 1
25 11 25 1
|
|---|
