| Entry |
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|---|
| Name |
Tolmetin (USAN/INN) |
|---|
| Formula |
C15H15NO3
|
|---|
| Exact mass |
257.1052
|
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| Mol weight |
257.2845
|
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
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| Remark |
| Product (DG00747): | D00158<US> |
|
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| Efficacy |
Anti-inflammatory, COX inhibitor |
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB03 Tolmetin
D02355 Tolmetin (USAN/INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA21 Tolmetin
D02355 Tolmetin (USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00747 Tolmetin
D02355 Tolmetin
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D02355 Tolmetin (USAN/INN)
PTGS2 (COX2)
D02355 Tolmetin (USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00747 Tolmetin
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| Other DBs |
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| KCF data |
ATOM 19
1 C8y C 22.2600 -21.7000
2 C5a C 21.0000 -21.1400
3 N4y N 23.3100 -20.8600
4 C8x C 22.7500 -23.0300
5 C8y C 19.7400 -21.7700
6 O5a O 21.0000 -19.7400
7 C8y C 24.5000 -21.6300
8 C1a C 23.3100 -19.3900
9 C8x C 24.0800 -23.0300
10 C8x C 18.5500 -21.0700
11 C8x C 19.7400 -23.1700
12 C1b C 25.8300 -21.0700
13 C8x C 17.3600 -21.7700
14 C8x C 18.5500 -23.8700
15 C6a C 26.8800 -21.7700
16 C8y C 17.3600 -23.1700
17 O6a O 28.3500 -21.1400
18 O6a O 26.8800 -23.1700
19 C1a C 16.1700 -23.8700
BOND 20
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 2
11 7 12 1
12 10 13 2
13 11 14 1
14 12 15 1
15 13 16 1
16 15 17 1
17 15 18 2
18 16 19 1
19 7 9 2
20 14 16 2
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