| Entry |
|
|---|
| Name |
Trimipramine maleate (JAN/USP);
Surmontil (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C20H26N2. C4H4O4
|
|---|
| Exact mass |
410.2206
|
|---|
| Mol weight |
410.506
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
|---|
| Remark |
| Therapeutic category: | 1174 |
| Product (DG00931): | D02408<JP/US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA06 Trimipramine
D02408 Trimipramine maleate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Antidepressants
Tricyclics
Trimipramine
D02408 Trimipramine maleate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1174 Imipramines
D02408 Trimipramine maleate (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00931 Trimipramine
D02408 Trimipramine maleate
DG01728 Tricyclic antidepressant
DG00931 Trimipramine
D02408 Trimipramine maleate
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
D02408 Trimipramine maleate
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D02408 Trimipramine maleate (JAN/USP) <JP/US>
SLC6A4 (HTT)
D02408 Trimipramine maleate (JAN/USP) <JP/US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D02408
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00931 Trimipramine
DG01728 Tricyclic antidepressant
DG00931 Trimipramine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 30
1 C6a C 38.9900 -19.7400
2 C2b C 38.2900 -18.6200
3 O6a O 38.2900 -20.9300
4 O6a O 40.3200 -19.7400
5 C2b C 36.6100 -18.6200
6 C6a C 35.9100 -19.7400
7 O6a O 34.5100 -19.7400
8 O6a O 36.6100 -20.9300
9 C1x C 26.5300 -22.2600
10 C8y C 25.6900 -21.1400
11 C8y C 26.0400 -19.8100
12 N1y N 27.3000 -19.2500
13 C1x C 27.9300 -22.2600
14 C8y C 28.5600 -19.8800
15 C8y C 28.8400 -21.2100
16 C8x C 24.9900 -18.8300
17 C8x C 23.6600 -19.2500
18 C8x C 23.3100 -20.5800
19 C8x C 24.3600 -21.5600
20 C8x C 30.1700 -21.6300
21 C8x C 31.2200 -20.7200
22 C8x C 30.9400 -19.3200
23 C8x C 29.6100 -18.9000
24 C1b C 27.3000 -17.8500
25 C1c C 28.5124 -17.1500
26 C1b C 29.7079 -17.8404
27 C1a C 28.5125 -15.7502
28 N1c N 30.8953 -17.1549
29 C1a C 32.0865 -17.8429
30 C1a C 30.8955 -15.7502
BOND 31
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 5 6 1
6 6 7 1
7 6 8 2
8 11 12 1
9 9 13 1
10 12 14 1
11 10 11 1
12 13 15 1
13 9 10 1
14 14 15 1
15 11 16 2
16 16 17 1
17 17 18 2
18 18 19 1
19 10 19 2
20 15 20 2
21 20 21 1
22 21 22 2
23 22 23 1
24 14 23 2
25 12 24 1
26 24 25 1
27 25 26 1
28 25 27 1
29 26 28 1
30 28 29 1
31 28 30 1
|
|---|
