| Entry |
|
|---|
| Name |
Artemether (JAN/USAN/INN) |
|---|
| Formula |
C16H26O5
|
|---|
| Exact mass |
298.178
|
|---|
| Mol weight |
298.3746
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Product (mixture): | D02484<JP/US> |
|
|---|
| Efficacy |
Antimalarial |
|---|
| Comment |
Artemisinin derivative
|
|---|
| Target |
Plasmodium falciparum ATP2C [KO: K01537] |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P01 ANTIPROTOZOALS
P01B ANTIMALARIALS
P01BE Artemisinin and derivatives, plain
P01BE02 Artemether
D02483 Artemether (JAN/USAN/INN)
Antimicrobials [BR:br08307]
Antiparasitics
Antmalarials
Artemisinin and derivatives
D02483 Artemether (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C1z C 19.5467 -15.4991
2 C1y C 18.3421 -16.1916
3 C1y C 20.7628 -16.2032
4 C1y C 19.5526 -14.1142
5 O2x O 17.9580 -15.3710
6 O2x O 17.0386 -15.6795
7 O2x O 18.3480 -17.5998
8 C1y C 20.7628 -17.5998
9 C1x C 21.9615 -15.5049
10 C1y C 20.7628 -13.4158
11 C1x C 18.8077 -13.0900
12 O2x O 17.9639 -13.9803
13 C1z C 16.6255 -14.3468
14 C1y C 19.5526 -18.2980
15 C1a C 21.9674 -18.2923
16 C1x C 21.9615 -14.1142
17 C1a C 20.7628 -12.0252
18 C1x C 17.4111 -13.0609
19 C1a C 15.2463 -14.3468
20 O2a O 19.5583 -19.6887
21 C1a C 18.3413 -20.3979
BOND 24
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Down
5 2 6 1
6 2 7 1
7 3 8 1
8 3 9 1
9 4 10 1
10 4 11 1
11 5 12 1
12 6 13 1
13 7 14 1
14 8 15 1 #Up
15 9 16 1
16 10 17 1 #Down
17 11 18 1
18 13 19 1
19 14 20 1 #Up
20 8 14 1
21 10 16 1
22 13 12 1 #Down
23 13 18 1
24 20 21 1
|
|---|
