KEGG   DRUG: Enfuvirtide
Entry
D02499                      Drug                                   
Name
Enfuvirtide (USAN/INN);
Fuzeon (TN)
  Abbr
EFV, T-20
Product
Formula
C204H301N51O64
Exact mass
4489.1866
Mol weight
4491.876
Sequence
Ac-Tyr Thr Ser Leu Ile His Ser Leu Ile Glu Glu Ser Gln Asn Gln
Gln Glu Lys Asn Glu Gln Glu Leu Leu Glu Leu Asp Lys Trp Ala Ser
Leu Trp Asn Trp Phe-NH2
  Type
Peptide
Class
Antiviral
 DG03107  Anti-HIV agent
Remark
ATC code: J05AX07
Product: D02499<US>
Efficacy
Antiviral, HIV-1 gp41 fusion inhibitor
  Disease
HIV-1 infection [DS:H01563]
Target
HIV-1 gp41 [KO:K24801]
  Pathway
ko03230  Viral genome structure
ko03250  Viral life cycle - HIV-1
Interaction
Structure map
map07053  Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AX Other antivirals
     J05AX07 Enfuvirtide
      D02499  Enfuvirtide (USAN/INN) <US>
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Other
   Enfuvirtide
    D02499  Enfuvirtide (USAN/INN)
Drug groups [BR:br08330]
 Antiviral
  DG03107  Anti-HIV agent
   D02499  Enfuvirtide
Drug classes [BR:br08332]
 Antiviral
  DG03107  Anti-HIV agent
   D02499  Enfuvirtide
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   HIV gp41/gp120
    D02499  Enfuvirtide (USAN/INN) <US>
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Entry, fusion or uncoating inhibitor
   HIV gp41/gp120
    D02499  Enfuvirtide (USAN/INN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D02499
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02499
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D02499
Other DBs
CAS: 159519-65-0
PubChem: 17396673
ChEBI: 608828
NIKKAJI: J2.173.441A

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