KEGG   DRUG: Fenticonazole nitrate
Entry
D02583                      Drug                                   
Name
Fenticonazole nitrate (USAN);
Lomexin (TN)
Formula
C24H20Cl2N2OS. HNO3
Exact mass
517.063
Mol weight
518.4122
Structure
Simcomp
Class
Antifungal
 DG01883  Imidazole antifungal
Remark
ATC code: D01AC12 G01AF12
Chemical structure group: DG00368
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Imidazole derivative
Target
sterol 14alpha-demethylase [KO:K05917]
  Pathway
ko00100  Steroid biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AC Imidazole and triazole derivatives
     D01AC12 Fenticonazole
      D02583  Fenticonazole nitrate (USAN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AF Imidazole derivatives
     G01AF12 Fenticonazole
      D02583  Fenticonazole nitrate (USAN)
Drug groups [BR:br08330]
 Antifungal
  DG01883  Imidazole antifungal
   DG00368  Fenticonazole
    D02583  Fenticonazole nitrate
Antimicrobials [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   Imidazole
    D02583  Fenticonazole nitrate (USAN)
Drug groups [BR:br08330]
 Antifungal
  DG01883  Imidazole antifungal
   DG00368  Fenticonazole
Other DBs
CAS: 73151-29-8
PubChem: 17396754
ChEBI: 83606
LigandBox: D02583
NIKKAJI: J311.650F
KCF data

ATOM        34
            1   C8y C    34.4521  -15.6263
            2   C1c C    34.4521  -14.2247
            3   C8y C    33.2375  -16.3271
            4   C8x C    35.6726  -16.3271
            5   C1b C    35.6669  -13.5182
            6   O2a O    33.2433  -13.5182
            7   C8x C    33.2375  -17.7287
            8   X   Cl   32.0110  -15.6263
            9   C8x C    35.6726  -17.7287
            10  N4y N    36.8756  -14.2306
            11  C1b C    32.0287  -14.2247
            12  C8y C    34.4521  -18.4352
            13  C8x C    37.9969  -13.3896
            14  C8x C    37.3226  -15.5478
            15  C8y C    30.8197  -13.5182
            16  X   Cl   34.4404  -19.8311
            17  C8x C    39.1282  -14.1972
            18  N5x N    38.7202  -15.5300
            19  C8x C    29.6109  -14.2247
            20  C8x C    30.8197  -12.1166
            21  C8x C    28.3903  -13.5182
            22  C8x C    29.6109  -11.4157
            23  C8y C    28.3903  -12.1166
            24  S2a S    27.1698  -11.4157
            25  C8y C    25.9600  -12.1182
            26  C8x C    24.7657  -11.4323
            27  C8x C    23.5535  -12.1357
            28  C8x C    23.4868  -13.5371
            29  C8x C    24.7511  -14.2230
            30  C8x C    25.9632  -13.5196
            31  N2b N    28.6649  -18.7448 #+
            32  O1b O    27.4560  -19.4339
            33  O3a O    28.6590  -17.3432
            34  O3a O    29.8737  -19.4456 #-
BOND        36
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11    7  12 2
            12   10  13 1
            13   10  14 1
            14   11  15 1
            15   12  16 1
            16   13  17 2
            17   14  18 2
            18   15  19 1
            19   15  20 2
            20   19  21 2
            21   20  22 1
            22   21  23 1
            23   23  24 1
            24    9  12 1
            25   17  18 1
            26   22  23 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   28  29 1
            32   29  30 2
            33   25  30 1
            34   31  32 1
            35   31  33 2
            36   31  34 1

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Ontology (3)   
   KEGG BRITE (3)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (1)   
   KEGG ORTHOLOGY (1)   
All databases (9)   

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