| Entry |
|
|---|
| Name |
Beraprost (USAN) |
|---|
| Formula |
C24H30O5
|
|---|
| Exact mass |
398.2093
|
|---|
| Mol weight |
398.492
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
|
|---|
| Remark |
| Product (DG00160): | D01551<JP> |
|
|---|
| Efficacy |
Platelet aggregation inhibitor, Prostaglandin I2 receptor agonist |
|---|
| Comment |
Prostacycline derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC19 Beraprost
D02720 Beraprost (USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00160 Beraprost
D02720 Beraprost
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
DG00160 Beraprost
D02720 Beraprost
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostacyclin
PTGIR
D02720 Beraprost (USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00160 Beraprost
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
DG00160 Beraprost
|
|---|
| Other DBs |
|
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| KCF data |
ATOM 29
1 C8y C 15.9561 -15.6378
2 C8y C 16.6542 -16.8944
3 C8x C 18.1203 -16.8944
4 C8x C 18.8184 -15.6378
5 C8x C 18.0505 -14.3812
6 C8y C 16.6542 -14.3812
7 C1y C 15.9561 -18.0812
8 C1y C 14.6297 -17.6624
9 C1y C 15.9561 -19.4775
10 O2x O 14.6297 -16.2661
11 C1x C 13.8617 -18.7794
12 C1y C 14.6995 -19.8964
13 C2b C 17.1429 -20.1756
14 O1a O 14.2108 -21.2926
15 C2b C 18.3297 -19.4775
16 C1c C 19.5165 -20.1756
17 C1c C 20.7034 -19.4775
18 O1a O 19.5165 -21.5719
19 C1b C 21.8902 -20.1756
20 C3b C 23.1469 -19.4775
21 C1a C 20.7034 -18.0812
22 C1b C 15.9561 -13.1944
23 C3b C 24.3337 -18.7794
24 C1a C 25.5205 -18.0812
25 C1b C 14.5599 -13.1944
26 C1b C 13.8617 -12.0076
27 C6a C 12.4655 -12.0076
28 O6a O 11.7674 -10.8207
29 O6a O 11.7674 -13.1944
BOND 31
1 7 9 1
2 7 2 1
3 8 10 1
4 8 11 1
5 9 12 1
6 9 13 1
7 12 14 1
8 13 15 2
9 15 16 1
10 16 17 1
11 16 18 1
12 17 19 1
13 19 20 1
14 10 1 1
15 11 12 1
16 5 6 2
17 17 21 1
18 6 1 1
19 6 22 1
20 1 2 2
21 2 3 1
22 3 4 2
23 4 5 1
24 20 23 3
25 7 8 1
26 23 24 1
27 22 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 27 29 2
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