| Entry |
|
|---|
| Name |
Adefovir (USAN/INN) |
|---|
| Formula |
C8H12N5O4P
|
|---|
| Exact mass |
273.0627
|
|---|
| Mol weight |
273.1857
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
|
|---|
| Remark |
| Product (DG01224): | D01655<US> |
|
|---|
| Efficacy |
Antiviral, Reverse transcriptase inhibitor |
|---|
| Target |
HBV reverse transcriptase [KO: K21037] |
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG01224 Adefovir
D02768 Adefovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
HBV reverse transcriptase inhibitor
D02768 Adefovir (USAN/INN)
Prodrugs [br08324.html]
D02768
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG01224 Adefovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
HBV reverse transcriptase inhibitor
DG01224 Adefovir
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C8y C 30.5268 -18.7216
2 C8y C 30.5268 -17.2550
3 N4y N 29.1998 -19.1407
4 N5x N 31.7839 -19.3502
5 N5x N 29.1998 -16.8359
6 C8y C 31.7839 -16.6263
7 C8x C 28.3617 -18.0232
8 C8x C 32.9713 -18.7216
9 N5x N 32.9713 -17.2550
10 N1a N 31.7839 -15.2295
11 C1b C 29.1998 -20.5407
12 C1b C 27.9935 -21.2370
13 O2a O 26.7745 -20.5331
14 C1b C 25.5469 -21.2424
15 P1b P 24.3227 -20.5365
16 O1c O 23.1102 -19.8365
17 O1c O 23.6264 -21.7427
18 O1c O 25.0255 -19.3188
BOND 19
1 2 5 1
2 2 6 1
3 3 7 1
4 4 8 2
5 6 9 2
6 5 7 2
7 8 9 1
8 1 2 2
9 1 3 1
10 1 4 1
11 6 10 1
12 3 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 15 17 1
19 15 18 2
|
|---|
