| Entry |
|
|---|
| Name |
Amorolfine (USAN/INN);
Loceryl (TN) |
|---|
| Formula |
C21H35NO
|
|---|
| Exact mass |
317.2719
|
|---|
| Mol weight |
317.5087
|
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| Structure |
|
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| Simcomp |
|
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| Remark |
| Product (DG00376): | D01720<JP> |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Morpholine derivative
|
|---|
| Target |
squalene epoxidase [KO: K00511] |
|---|
| Pathway |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AE Other antifungals for topical use
D01AE16 Amorolfine
D02923 Amorolfine (USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Amorolfine
D02923 Amorolfine (USAN/INN)
Second-class OTC drugs
Inorganic and organic chemicals
Amorolfine
D02923 Amorolfine (USAN/INN)
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Other ergosterol biosynthesis inhibitor
D02923 Amorolfine (USAN/INN)
|
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| Other DBs |
|
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| KCF data |
ATOM 23
1 C8y C 17.8290 -17.2793
2 C8x C 17.8290 -18.6727
3 C8x C 19.0830 -19.3695
4 C8y C 20.2674 -18.6727
5 C8x C 20.2674 -17.2793
6 C8x C 19.0830 -16.5827
7 C1b C 21.4518 -19.3695
8 C1c C 22.6360 -18.6727
9 C1b C 23.8901 -19.3695
10 N1y N 25.0744 -18.6727
11 C1x C 26.2588 -19.3695
12 C1y C 27.5131 -18.6727
13 C1a C 22.6360 -17.2793
14 C1x C 25.0744 -17.2793
15 C1y C 26.2588 -16.5827
16 O2x O 27.5129 -17.2793
17 C1d C 16.6446 -16.5827
18 C1b C 16.6446 -15.1893
19 C1a C 15.3906 -17.2793
20 C1a C 17.6199 -15.6073
21 C1a C 15.3906 -14.4926
22 C1a C 26.2411 -15.1647
23 C1a C 28.7168 -19.4018
BOND 24
1 4 5 1
2 11 12 1
3 5 6 2
4 6 1 1
5 8 13 1
6 10 14 1
7 4 7 1
8 14 15 1
9 12 16 1
10 7 8 1
11 15 16 1
12 1 2 2
13 1 17 1
14 8 9 1
15 17 18 1
16 2 3 1
17 17 19 1
18 9 10 1
19 17 20 1
20 3 4 2
21 18 21 1
22 10 11 1
23 15 22 1 #Down
24 12 23 1 #Down
|
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