| Entry |
|
|---|
| Name |
Arbutamine hydrochloride (USAN);
Genesa (TN) |
|---|
| Formula |
C18H23NO4. HCl
|
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| Exact mass |
353.1394
|
|---|
| Mol weight |
353.8405
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Cardiotonic, beta-Adrenergic receptor agonist |
|---|
| Comment |
Catecholamine derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA22 Arbutamine
D02976 Arbutamine hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
D02976 Arbutamine hydrochloride
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
D02976 Arbutamine hydrochloride
DG01951 Catecholamine adrenergic receptor agonist
D02976 Arbutamine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D02976 Arbutamine hydrochloride (USAN)
|
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| Other DBs |
|
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| KCF data |
ATOM 24
1 C8x C 12.1800 -17.5700
2 C8y C 12.1800 -16.1700
3 C8x C 10.9900 -15.4700
4 C8y C 9.7300 -16.1700
5 C8y C 9.7300 -17.5700
6 C8x C 10.9900 -18.2700
7 O1a O 8.5400 -18.2700
8 O1a O 8.5400 -15.4700
9 C1c C 13.3700 -15.4700
10 C1b C 14.6300 -16.1700
11 N1b N 15.8900 -15.4700
12 C1b C 17.0100 -16.1700
13 C1b C 18.2700 -15.4700
14 C1b C 19.4600 -16.1700
15 C1b C 20.6500 -15.4700
16 C8y C 21.9100 -16.1700
17 C8x C 23.1000 -15.4700
18 C8x C 24.2900 -16.1700
19 O1a O 13.3700 -14.0700
20 C8x C 21.9100 -17.5700
21 C8x C 23.1000 -18.2700
22 C8y C 24.2900 -17.5700
23 O1a O 25.4800 -18.2700
24 X Cl 28.7000 -17.0800
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 4 8 1
9 2 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 2
19 9 19 1 #Up
20 16 20 2
21 20 21 1
22 21 22 2
23 22 18 1
24 22 23 1
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