| Entry |
|
|---|
| Name |
Clorgiline (INN);
Clorgyline |
|---|
| Formula |
C13H15Cl2NO
|
|---|
| Exact mass |
271.0531
|
|---|
| Mol weight |
272.1703
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase A (MAO-A) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00330 | Arginine and proline metabolism |
| hsa00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07216 | Catecholamine transferase inhibitors |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
D03248 Clorgiline
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAOA
D03248 Clorgiline (INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 17
1 C1b C 25.5302 -19.1297
2 N1c N 25.5302 -20.5361
3 C1b C 26.7382 -21.2247
4 C1a C 24.3163 -21.2306
5 C3b C 27.9519 -20.5244
6 C3a C 29.1162 -19.7510
7 C1b C 24.3251 -18.4176
8 C8y C 20.6990 -19.1072
9 O2a O 21.9070 -18.4129
10 C8x C 20.6990 -20.5135
11 C8y C 19.4853 -18.4070
12 C8x C 19.4853 -21.2138
13 C8x C 18.2656 -19.1072
14 C8y C 18.2656 -20.5135
15 C1b C 23.1146 -19.1133
16 X Cl 19.4866 -17.0108
17 X Cl 17.0573 -21.2131
BOND 17
1 2 4 1
2 3 5 1
3 5 6 3
4 8 9 1
5 8 10 1
6 8 11 2
7 10 12 2
8 11 13 1
9 12 14 1
10 13 14 2
11 7 1 1
12 9 15 1
13 15 7 1
14 1 2 1
15 11 16 1
16 2 3 1
17 14 17 1
|
|---|
