 | | DRUG: Desonide | |
| Entry |
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| Name |
Desonide (USP/INN);
Desowen (TN);
Verdeso (TN) |
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| Product |
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| Generic |
DESONIDE (Actavis Pharma), DESONIDE (Advanced Rx Pharmacy of Tennessee), DESONIDE (Alembic Pharmaceuticals), DESONIDE (Alembic Pharmaceuticals), DESONIDE (Alembic Pharmaceuticals), DESONIDE (Bryant Ranch Prepack), DESONIDE (Bryant Ranch Prepack), DESONIDE (Bryant Ranch Prepack), DESONIDE (Bryant Ranch Prepack), DESONIDE (Cintex Services), DESONIDE (Cosette Pharmaceuticals), DESONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), DESONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), DESONIDE (NORTHSTAR RX LLC), DESONIDE (NORTHSTAR RX LLC), DESONIDE (Northstar Rx LLC), DESONIDE (Proficient Rx LP), DESONIDE (Taro Pharmaceuticals U.S.A.), DESONIDE (Taro Pharmaceuticals U.S.A.), DESONIDE (Viona Pharmaceuticals), DESONIDE (Zydus Lifesciences Limited), DESONIDE OINTMENT, 0.05% (Bryant Ranch Prepack), DESONIDE OINTMENT, 0.05% (Bryant Ranch Prepack), DESONIDE OINTMENT, 0.05% (Bryant Ranch Prepack), DESONIDE OINTMENT, 0.05% (Encube Ethicals Private Limited) |
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| Formula |
C24H32O6
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| Exact mass |
416.2199
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| Mol weight |
416.5073
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Disease |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB08 Desonide
D03696 Desonide (USP/INN) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA11 Desonide
D03696 Desonide (USP/INN) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, Low Potency
Desonide
D03696 Desonide (USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D03696 Desonide
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D03696 Desonide
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D03696 Desonide (USP/INN) <US>
Topical steroids potency [br08317.html]
Classification in the USA
D03696
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| Other DBs |
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| KCF data |
ATOM 30
1 C2x C 29.0870 -20.6780
2 C5x C 29.0870 -22.0509
3 C2x C 30.2760 -22.7374
4 C2y C 31.4650 -22.0509
5 C1z C 31.4650 -20.6780
6 C2x C 30.2760 -19.9916
7 C1x C 32.6539 -22.7374
8 C1x C 33.8429 -22.0509
9 C1y C 33.8429 -20.6780
10 C1y C 32.6539 -19.9916
11 C1y C 35.0319 -19.9916
12 C1z C 35.0319 -18.6187
13 C1x C 33.8429 -17.9322
14 C1y C 32.6539 -18.6187
15 C1x C 37.4098 -19.9916
16 C1y C 37.4098 -18.6187
17 C1z C 36.2208 -17.9322
18 O2x O 38.7827 -18.6187
19 C1z C 38.7827 -17.2458
20 C1a C 38.7827 -15.8728
21 O2x O 37.4098 -17.2458
22 C1a C 40.1556 -17.2458
23 C5a C 36.2208 -16.2793
24 O5a O 37.4138 -15.5906
25 C1b C 35.0358 -15.5951
26 O5x O 27.8981 -22.7374
27 C1a C 31.4650 -19.3051
28 O1a O 31.4670 -17.9334
29 C1a C 35.0319 -17.2458
30 O1a O 33.8431 -16.2843
BOND 34
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 16 18 1 #Down
22 18 19 1
23 19 20 1
24 17 21 1 #Down
25 21 19 1
26 19 22 1
27 17 23 1 #Up
28 23 24 2
29 23 25 1
30 2 26 2
31 5 27 1 #Up
32 14 28 1 #Up
33 12 29 1 #Up
34 25 30 1
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