 | | DRUG: Desoximetasone | |
| Entry |
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| Name |
Desoximetasone (USP/INN);
Topicort (TN) |
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| Product |
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| Generic |
DESOXIMETASONE (A-S Medication Solutions), DESOXIMETASONE (A-S Medication Solutions), DESOXIMETASONE (Actavis Pharma), DESOXIMETASONE (Actavis Pharma), DESOXIMETASONE (Bryant Ranch Prepack), DESOXIMETASONE (Bryant Ranch Prepack), DESOXIMETASONE (Bryant Ranch Prepack), DESOXIMETASONE (Bryant Ranch Prepack), DESOXIMETASONE (E. Fougera & Co. a division of Fougera Pharmaceuticals), DESOXIMETASONE (E. Fougera & Co. a division of Fougera Pharmaceuticals), DESOXIMETASONE (Glenmark Pharmaceuticals), DESOXIMETASONE (Lupin Pharmaceuticals), DESOXIMETASONE (Lupin Pharmaceuticals), DESOXIMETASONE (Lupin Pharmaceuticals), DESOXIMETASONE (Lupin Pharmaceuticals), DESOXIMETASONE (Lupin Pharmaceuticals), DESOXIMETASONE (Novel Laboratories), DESOXIMETASONE (Padagis Israel Pharmaceuticals), DESOXIMETASONE (Padagis Israel Pharmaceuticals), DESOXIMETASONE (Padagis Israel Pharmaceuticals), DESOXIMETASONE (Proficient Rx LP), DESOXIMETASONE (Proficient Rx LP), DESOXIMETASONE (RPK Pharmaceuticals), DESOXIMETASONE (Taro Pharmaceuticals U.S.A.), DESOXIMETASONE (Taro Pharmaceuticals U.S.A.), DESOXIMETASONE (Taro Pharmaceuticals U.S.A.), DESOXIMETASONE (Viona Pharmaceuticals), DESOXIMETASONE (Viona Pharmaceuticals), DESOXIMETASONE (Zydus Lifesciences Limited), DESOXIMETASONE (Zydus Lifesciences Limited), TOPICORT (Taro Pharmaceuticals U.S.A.), TOPICORT (Taro Pharmaceuticals U.S.A.) |
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| Formula |
C22H29FO4
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| Exact mass |
376.205
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| Mol weight |
376.4617
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Disease |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC03 Desoximetasone
D03697 Desoximetasone (USP/INN) <US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XC Corticosteroids, potent, other combinations
D07XC02 Desoximetasone
D03697 Desoximetasone (USP/INN) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, Medium Potency
Desoximetasone
D03697 Desoximetasone (USP/INN)
Glucocorticoids, High Potency
Desoximetasone
D03697 Desoximetasone (USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D03697 Desoximetasone
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D03697 Desoximetasone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D03697 Desoximetasone (USP/INN) <US>
Topical steroids potency [br08317.html]
Classification in the USA
D03697
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| Other DBs |
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| KCF data |
ATOM 27
1 C2x C 24.2900 -24.2900
2 C5x C 24.2900 -25.6900
3 C2x C 25.5024 -26.3900
4 C2y C 26.7149 -25.6900
5 C1z C 26.7149 -24.2900
6 C2x C 25.5024 -23.5900
7 C1x C 27.9273 -26.3900
8 C1x C 29.1397 -25.6900
9 C1y C 29.1397 -24.2900
10 C1z C 27.9273 -23.5900
11 C1y C 30.3522 -23.5900
12 C1z C 30.3522 -22.1900
13 C1x C 29.1397 -21.4900
14 C1y C 27.9273 -22.1900
15 C1x C 32.7770 -23.5900
16 C1y C 32.7770 -22.1900
17 C1y C 31.5646 -21.4900
18 C1a C 33.9766 -21.4973
19 C5a C 31.5646 -19.8800
20 C1a C 30.3522 -20.7900
21 O1a O 26.7169 -21.4912
22 C1a C 26.7149 -22.8900
23 X F 27.9273 -24.9900
24 O5x O 23.0776 -26.3900
25 O5a O 32.7811 -19.1777
26 C1b C 30.3562 -19.1823
27 O1a O 29.1627 -19.8716
BOND 30
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 16 18 1 #Down
22 17 19 1 #Up
23 12 20 1 #Up
24 14 21 1 #Up
25 5 22 1 #Up
26 10 23 1 #Down
27 2 24 2
28 19 25 2
29 19 26 1
30 26 27 1
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