KEGG   DRUG: Dexbrompheniramine maleate
Entry
D03704                      Drug                                   
Name
Dexbrompheniramine maleate (USP);
Disomer (TN)
Formula
C16H19BrN2. C4H4O4
Exact mass
434.0841
Mol weight
435.3116
Structure
Simcomp
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: R06AB06
Efficacy
Antiallergic, H1 receptor antagonist
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB06 Dexbrompheniramine
      D03704  Dexbrompheniramine maleate (USP)
Drug groups [BR:br08330]
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    D03704  Dexbrompheniramine maleate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D03704  Dexbrompheniramine maleate (USP)
Rx-to-OTC switch list in the USA [br08315.html]
 D03704
Other DBs
CAS: 2391-03-9
PubChem: 17397795
ChEBI: 59273
LigandBox: D03704
KCF data

ATOM        27
            1   C1c C    23.7694  -15.7265
            2   C8y C    24.9776  -16.4152
            3   C1b C    23.7751  -14.3200
            4   C8x C    24.9776  -17.8218
            5   N5x N    26.1856  -15.7089
            6   C1b C    24.9776  -13.6313
            7   C8x C    26.1856  -18.5164
            8   C8x C    27.4054  -16.4152
            9   N1c N    24.9716  -12.2305
            10  C8x C    27.4054  -17.8218
            11  C1a C    23.7577  -11.5243
            12  C1a C    26.1856  -11.5126
            13  C8y C    22.5612  -16.4386
            14  C8x C    21.3414  -15.7439
            15  C8x C    22.5729  -17.8334
            16  C8x C    20.1390  -16.4560
            17  C8x C    21.3647  -18.5398
            18  C8y C    20.1506  -17.8568
            19  X   Br   18.9368  -18.5631
            20  C2b C    33.0025  -14.2030
            21  C2b C    31.3683  -14.2087
            22  C6a C    33.6795  -15.3761
            23  C6a C    30.6913  -15.3878
            24  O6a O    33.0084  -16.5493
            25  O6a O    35.0453  -15.4344
            26  O6a O    29.3314  -15.3878
            27  O6a O    31.3800  -16.5609
BOND        27
            1     1   2 1
            2     1   3 1 #Down
            3     2   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 2
            7     5   8 1
            8     6   9 1
            9     7  10 1
            10    9  11 1
            11    9  12 1
            12    8  10 2
            13   13  14 1
            14   13  15 2
            15   14  16 2
            16   15  17 1
            17   16  18 1
            18   18  19 1
            19   17  18 2
            20    1  13 1
            21   20  21 2
            22   20  22 1
            23   21  23 1
            24   22  24 1
            25   22  25 2
            26   23  26 1
            27   23  27 2

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   KEGG BRITE (4)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (2)   
   PubChem (1)   
   ChEBI (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (11)   

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