| Entry |
|
|---|
| Name |
Dextroamphetamine (USAN);
Dexamfetamine (INN);
Xelstrym (TN) |
|---|
| Product |
|
|---|
| Formula |
C9H13N
|
|---|
| Exact mass |
135.1048
|
|---|
| Mol weight |
135.2062
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
| Product (DG00967): | D03740<US> D02078<US> |
|
|---|
| Efficacy |
Stimulant (central) |
|---|
| Disease |
Attention deficit hyperactivity disorder [DS: H01895] |
|---|
| Comment |
Compoment of Biphetamine (TN)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA02 Dexamfetamine
D03740 Dextroamphetamine (USAN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00967 Dexamfetamine
D03740 Dextroamphetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00967 Dexamfetamine
D03740 Dextroamphetamine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D03740 Dextroamphetamine (USAN) <US>
SLC6A3 (DAT1)
D03740 Dextroamphetamine (USAN) <US>
SLC18
SLC18A2 (VMAT2)
D03740 Dextroamphetamine (USAN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03740
Prodrugs [br08324.html]
D03740
Narcotics and psychotropics in Japan [br08308.html]
Stimulants by Control Act Article 2 Appended Table and Cabinet Order
D03740
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00967 Dexamfetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00967 Dexamfetamine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 10
1 C8y C 18.0875 -15.2739
2 C8x C 16.8262 -14.5732
3 C8x C 18.0875 -16.6754
4 C1b C 19.2786 -14.5732
5 C8x C 15.6350 -15.2739
6 C8x C 16.8262 -17.3761
7 C1c C 20.4698 -15.2739
8 C8x C 15.6350 -16.6754
9 N1a N 21.6609 -14.5732
10 C1a C 20.4695 -16.6597
BOND 10
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 5 8 2
8 7 9 1
9 6 8 1
10 7 10 1 #Up
|
|---|
