| Entry |
|
|---|
| Name |
Perindopril (USAN/INN) |
|---|
| Formula |
C19H32N2O5
|
|---|
| Exact mass |
368.2311
|
|---|
| Mol weight |
368.4678
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
| Product (DG00337): | D00624<JP/US> |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Comment |
Active form of prodrug: Perindoprilat [CPD: C21517]
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA04 Perindopril
D03753 Perindopril (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
D03753 Perindopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
D03753 Perindopril
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D03753 Perindopril (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
Prodrugs [br08324.html]
DG00337
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 26
1 N1y N 36.2600 -19.6700
2 C1y C 37.5900 -20.2300
3 C1y C 36.4700 -18.2700
4 C5a C 35.0700 -20.3700
5 C1y C 38.5000 -19.1800
6 C1x C 38.0100 -21.5600
7 C1x C 37.8000 -17.9200
8 C6a C 36.4000 -16.8700
9 C1c C 33.8800 -19.6700
10 O5a O 35.0700 -21.7700
11 C1x C 39.9000 -19.4600
12 C1x C 39.3400 -21.8400
13 O6a O 37.6600 -16.1000
14 O6a O 35.2100 -16.1700
15 N1b N 32.6200 -20.3700
16 C1a C 33.8800 -18.2700
17 C1x C 40.3200 -20.7900
18 C1c C 31.4300 -19.6700
19 C7a C 31.4300 -18.2700
20 C1b C 30.2400 -20.3700
21 O7a O 32.6200 -17.5700
22 O6a O 30.2400 -17.5700
23 C1b C 28.9800 -19.6700
24 C1b C 32.6200 -16.1700
25 C1a C 27.7900 -20.3700
26 C1a C 31.4300 -15.4700
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1 #Down
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 1
12 8 13 1
13 8 14 2
14 9 15 1
15 9 16 1 #Up
16 11 17 1
17 15 18 1
18 18 19 1 #Up
19 18 20 1
20 19 21 1
21 19 22 2
22 20 23 1
23 21 24 1
24 23 25 1
25 24 26 1
26 5 7 1
27 12 17 1
|
|---|
