| Entry |
|
|---|
| Name |
Difenoxin (USAN/INN) |
|---|
| Formula |
C28H28N2O2
|
|---|
| Exact mass |
424.2151
|
|---|
| Mol weight |
424.5341
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiarrheal, Antiperistaltic, Opioid receptor agonist |
|---|
| Comment |
Component of Motofen (TN)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07D ANTIPROPULSIVES
A07DA Antipropulsives
A07DA04 Difenoxin
D03809 Difenoxin (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG03054 Difenoxin
D03809 Difenoxin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D03809 Difenoxin (USAN/INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Cabinet Order Article 1 (157 substances)
D03809
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG03054 Difenoxin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 32
1 C1d C 28.1731 -18.1265
2 C8y C 26.9966 -18.8122
3 C8y C 29.3497 -18.8182
4 C1b C 28.1092 -16.7665
5 C3b C 26.6536 -17.2926
6 C8x C 26.9966 -20.1721
7 C8x C 25.8201 -18.1265
8 C8x C 29.3438 -20.1721
9 C8x C 30.5322 -18.1265
10 C1b C 29.2857 -16.0867
11 N3a N 25.1048 -16.4591
12 C8x C 25.8201 -20.8520
13 C8x C 24.6436 -18.8122
14 C8x C 30.5262 -20.8520
15 C8x C 31.7026 -18.8182
16 N1y N 29.2857 -14.7268
17 C8x C 24.6436 -20.1721
18 C8x C 31.7026 -20.1779
19 C1x C 30.4681 -14.0586
20 C1x C 28.1092 -14.0586
21 C1x C 30.4681 -12.6930
22 C1x C 28.1092 -12.6930
23 C1z C 29.2857 -12.0072
24 C6a C 30.5165 -11.2965
25 C8y C 28.0548 -11.2965
26 C8x C 28.0548 -9.8762
27 C8x C 26.8239 -9.1655
28 C8x C 25.5930 -9.8762
29 C8x C 25.5930 -11.2965
30 C8x C 26.8239 -12.0072
31 O6a O 31.7450 -12.0057
32 O6a O 30.5165 -9.8759
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 2
8 3 9 1
9 4 10 1
10 5 11 3
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 2
15 10 16 1
16 12 17 1
17 14 18 2
18 16 19 1
19 16 20 1
20 19 21 1
21 20 22 1
22 21 23 1
23 13 17 2
24 15 18 1
25 22 23 1
26 23 24 1
27 23 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 25 30 1
34 24 31 1
35 24 32 2
|
|---|
