KEGG   DRUG: Peramivir
Entry
D03829                      Drug                                   
Name
Peramivir (USAN/INN);
Peramivir hydrate (JAN);
Rapivab (TN)
  Abbr
PRV
Product
Formula
C15H28N4O4. 3H2O
Exact mass
382.2427
Mol weight
382.4531
Structure
Class
Antiviral
 DG03029  Anti-influenza virus agent
  DG02842  Neuraminidase inhibitor
Remark
Therapeutic category: 6250
ATC code: J05AH03
Product: D03829<JP/US>
Efficacy
Antiviral, Neuraminidase inhibitor
  Disease
Influenza [DS:H00398]
Target
Influenza A/B virus neuraminidase [KO:K19392]
  Pathway
ko03230  Viral genome structure
ko05164  Influenza A
Structure map
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AH Neuraminidase inhibitors
     J05AH03 Peramivir
      D03829  Peramivir (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Antivirals
  Anti-influenza Agents
   Peramivir
    D03829  Peramivir (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D03829  Peramivir (USAN/INN); Peramivir hydrate (JAN)
Drug groups [BR:br08330]
 Antiviral
  DG03029  Anti-influenza virus agent
   DG02842  Neuraminidase inhibitor
    D03829  Peramivir
Drug classes [BR:br08332]
 Antiviral
  DG03029  Anti-influenza virus agent
   D03829  Peramivir
Antimicrobials [BR:br08307]
 Antivirals
  Virus release inhibitor
   Neuraminidase inhibitor
    D03829  Peramivir (USAN/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Virus release inhibitor
   Neuraminidase inhibitor
    D03829  Peramivir (USAN/INN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D03829
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D03829
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D03829
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D03829
Other DBs
PubChem: 17397915
ChEBI: 85196
LigandBox: D03829
KCF data

ATOM        26
            1   O0  O    23.6750  -19.3192
            2   C1y C    15.8900  -16.2400
            3   C1y C    17.2900  -16.2400
            4   C1y C    17.7226  -14.9085
            5   C1y C    16.5900  -14.0856
            6   C1x C    15.4574  -14.9085
            7   N1b N    14.6776  -16.9400
            8   C2c C    13.4651  -16.2400
            9   N1a N    12.2527  -16.9400
            10  C1c C    18.5024  -16.9400
            11  C1c C    19.7149  -16.2400
            12  C1b C    20.9273  -16.9400
            13  C1a C    22.1397  -16.2400
            14  C6a C    16.5900  -12.6700
            15  O6a O    15.3776  -11.9700
            16  O6a O    17.8024  -11.9700
            17  N2a N    13.4651  -14.8402
            18  N1b N    18.5024  -18.3398
            19  C5a C    17.2732  -19.0496
            20  O5a O    16.0693  -18.3546
            21  C1a C    17.2734  -20.4399
            22  C1b C    19.7149  -14.8402
            23  C1a C    20.9461  -14.1292
            24  O1a O    19.0422  -14.4797
            25  O0  O    23.6750  -19.3192
            26  O0  O    23.6750  -19.3192
BOND        23
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     2   6 1
            6     2   7 1 #Down
            7     7   8 1
            8     8   9 1
            9     3  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13    5  14 1 #Down
            14   14  15 2
            15   14  16 1
            16    8  17 2
            17   10  18 1 #Down
            18   18  19 1
            19   19  20 2
            20   19  21 1
            21   11  22 1
            22   22  23 1
            23    4  24 1 #Up
BRACKET     1    21.4900  -20.1600   21.4900  -18.2700
            1    24.2900  -18.2700   24.2900  -20.1600
            1  3
 ORIGINAL  1    1
 REPEAT    1   26  27

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