KEGG   DRUG: Exenatide
Entry
D04121                      Drug                                   
Name
Exenatide (JAN/USAN/INN);
Byetta (TN)
Product
Formula
C184H282N50O60S
Exact mass
4184.0273
Mol weight
4186.5719
Sequence
His Gly Glu Gly Thr Phe Thr Ser Asp Leu Ser Lys Gln Met Glu Glu
Glu Ala Val Arg Leu Phe Ile Glu Trp Leu Lys Asn Gly Gly Pro Ser
Ser Gly Ala Pro Pro Pro Ser
  Type
Peptide
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01493  GLP-1 receptor agonist
Remark
Same as: C15894
Therapeutic category: 2499
ATC code: A10BJ01
Product: D04121<JP/US>
Efficacy
Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
GLP-1 [CPD:C16048] analog
Target
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
Interaction
Structure map
map07051  Antidiabetics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BJ Glucagon-like peptide-1 (GLP-1) analogues
     A10BJ01 Exenatide
      D04121  Exenatide (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   GLP-1 Receptor Agonist
    Exenatide
     D04121  Exenatide (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D04121  Exenatide (JAN/USAN/INN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01493  GLP-1 receptor agonist
    D04121  Exenatide
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01493  GLP-1 receptor agonist
   D04121  Exenatide
  DG02044  Hypoglycemic agent
   D04121  Exenatide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D04121  Exenatide (JAN/USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D04121
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D04121
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D04121
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D04121
Other DBs
CAS: 141758-74-9
PubChem: 47206069
ChEBI: 64073
NIKKAJI: J1.038.138J

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