KEGG   DRUG: Forasartan
Entry
D04243                      Drug                                   
Name
Forasartan (USAN/INN)
Formula
C23H28N8
Exact mass
416.2437
Mol weight
416.522
Structure
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
  DG01495  Angiotensin II receptor antagonist
 DG03231  Antihypertensive
  DG01495  Angiotensin II receptor antagonist
Efficacy
Antihypertensive, Angiotensin II receptor antagonist
Target
AGTR1 [HSA:185] [KO:K04166]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04614  Renin-angiotensin system
Interaction
Brite
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01925  Renin-angiotensin system inhibitor
   DG01495  Angiotensin II receptor antagonist
    D04243  Forasartan
  DG03231  Antihypertensive
   DG01495  Angiotensin II receptor antagonist
    D04243  Forasartan
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Angiotensin
    AGTR1
     D04243  Forasartan (USAN/INN)
Other DBs
CAS: 145216-43-9
PubChem: 47206189
ChEBI: 141552
LigandBox: D04243
NIKKAJI: J557.449H
KCF data

ATOM        31
            1   C8x C    22.0500  -21.0000
            2   C8y C    23.2400  -21.7000
            3   C8x C    20.7900  -21.7000
            4   C8x C    23.2400  -23.1000
            5   C1b C    24.4300  -21.0000
            6   C8y C    20.7900  -23.1000
            7   N5x N    22.0500  -23.8000
            8   C8y C    19.6000  -23.8000
            9   C8y C    18.3400  -23.1000
            10  C8x C    17.1500  -23.8000
            11  C8x C    17.1500  -25.2000
            12  C8x C    18.4100  -25.9000
            13  C8x C    19.6000  -25.2000
            14  C8y C    18.3400  -21.7000
            15  N5x N    19.5300  -20.8600
            16  N5x N    19.0400  -19.4600
            17  N5x N    17.6400  -19.4600
            18  N4x N    17.2200  -20.8600
            19  N4y N    25.6481  -21.6901
            20  N5x N    26.0775  -23.0231
            21  C8y C    27.4839  -23.0259
            22  N5x N    27.9211  -21.6892
            23  C8y C    26.7850  -20.8604
            24  C1b C    26.7848  -19.4602
            25  C1b C    28.0161  -18.7491
            26  C1b C    28.0157  -17.3601
            27  C1a C    29.2162  -16.6666
            28  C1b C    28.3152  -24.1753
            29  C1b C    29.7500  -24.1449
            30  C1b C    30.4777  -25.3460
            31  C1a C    31.8498  -25.3169
BOND        34
            1     1   2 2
            2     1   3 1
            3     2   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 2
            7     6   8 1
            8     6   7 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    9  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   14  18 1
            21    5  19 1
            22   19  20 1
            23   20  21 2
            24   21  22 1
            25   22  23 2
            26   19  23 1
            27   23  24 1
            28   24  25 1
            29   25  26 1
            30   26  27 1
            31   21  28 1
            32   28  29 1
            33   29  30 1
            34   30  31 1

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  All links  
Ontology (2)   
   KEGG BRITE (2)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (4)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   NIKKAJI (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (10)   

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