KEGG   DRUG: Fosfomycin
Entry
D04253                      Drug                                   
Name
Fosfomycin (USAN/INN);
Phosphonomycin
Formula
C3H7O4P
Exact mass
138.0082
Mol weight
138.059
Structure
Simcomp
Source
Streptomyces [TAX:1883], Streptomyces fradiae [TAX:1906]
Remark
Same as: C06454
ATC code: J01XX01 S02AA17
Chemical structure group: DG00633
Product (DG00633): D00925<US> D02187<JP> D02188<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase [KO:K00790]
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX01 Fosfomycin
      D04253  Fosfomycin (USAN/INN)
 S SENSORY ORGANS
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA17 Fosfomycin
      D04253  Fosfomycin (USAN/INN)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    D04253  Fosfomycin (USAN/INN)
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    DG00633  Fosfomycin
Other DBs
CAS: 23155-02-4
PubChem: 47206194
ChEBI: 28915
PDB-CCD: FCN[PDBj]
LigandBox: D04253
NIKKAJI: J34.117G
KCF data

ATOM        8
            1   C1y C    18.4271   -7.9889
            2   C1y C    19.8321   -7.9889
            3   O2x O    19.1260   -6.7808
            4   P1b P    17.2055   -8.6936
            5   C1a C    21.0259   -8.6740
            6   O1c O    15.9931   -9.3936
            7   O1c O    16.5035   -7.4773
            8   O1c O    17.9030   -9.9021
BOND        8
            1     1   2 1
            2     2   3 1
            3     3   1 1
            4     1   4 1 #Up
            5     2   5 1 #Up
            6     4   6 2
            7     4   7 1
            8     4   8 1

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