| Entry |
|
|---|
| Name |
Mechlorethamine hydrochloride (USP);
Chlormethine hydrochloride;
Mustargen (TN);
Valchlor (TN) |
|---|
| Product |
|
|---|
| Formula |
C5H11Cl2N. HCl
|
|---|
| Exact mass |
191.0035
|
|---|
| Mol weight |
192.5145
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
|
|---|
| Remark |
| Product (DG00677): | D04872<US> |
|
|---|
| Efficacy |
Antineoplastic, Alkylating agent |
|---|
| Disease |
Mycosis fungoides-type cutaneous T-cell lymphoma [DS: H01463] |
|---|
| Comment |
Mechlorethamine is called Chlormethine in INN.
Nitrogen mustard
|
|---|
| Target |
DNA |
|---|
| Interaction |
|
|---|
| Structure map |
| map07040 | Antineoplastics - alkylating agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA05 Chlormethine
D04872 Mechlorethamine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Antineoplastics
Alkylating Agents
Mechlorethamine
D04872 Mechlorethamine hydrochloride (USP)
Dermatological Agents
Dermatological Agents, Other
Dermatological Agents, Miscellaneous
Mechlorethamine
D04872 Mechlorethamine hydrochloride (USP)
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00677 Chlormethine
D04872 Mechlorethamine hydrochloride
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00677 Chlormethine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 9
1 N1c N 25.6900 -18.6546
2 C1b C 24.4792 -17.9562
3 C1b C 26.9008 -17.9562
4 C1a C 25.6900 -20.0576
5 C1b C 23.2626 -18.6546
6 C1b C 28.1174 -18.6546
7 X Cl 22.0517 -17.9562
8 X Cl 29.3283 -17.9562
9 X Cl 32.4100 -19.3900
BOND 7
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 5 7 1
7 6 8 1
|
|---|
