| Entry |
|
|---|
| Name |
Methohexital (USP/INN) |
|---|
| Formula |
C14H18N2O3
|
|---|
| Exact mass |
262.1317
|
|---|
| Mol weight |
262.3043
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
|
|---|
| Remark |
| Product (DG00789): | D00712<US> |
|
|---|
| Efficacy |
Anesthetic, Sedative-hypnotic |
|---|
| Comment |
Barbituric acid derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AF Barbiturates, plain
N01AF01 Methohexital
D04985 Methohexital (USP/INN)
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CA Barbiturates, plain
N05CA15 Methohexital
D04985 Methohexital (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00789 Methohexital
D04985 Methohexital
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG00789 Methohexital
D04985 Methohexital
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABRA1
D04985 Methohexital (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00789 Methohexital
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG00789 Methohexital
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C1z C 21.1374 -16.1390
2 C5x C 21.1374 -17.5446
3 C5x C 19.9241 -15.4389
4 C1c C 22.5257 -16.1390
5 C1b C 21.1316 -14.7449
6 N1y N 19.9241 -18.2447
7 O5x O 22.3449 -18.2447
8 N1x N 18.7050 -16.1390
9 O5x O 19.9825 -14.0332
10 C3b C 23.2257 -14.9315
11 C1a C 23.5233 -17.1306
12 C2b C 22.3449 -14.0390
13 C5x C 18.7050 -17.5446
14 C1a C 19.9825 -19.6446
15 C2a C 22.3449 -12.6449
16 O5x O 17.4859 -18.2330
17 C3b C 23.8204 -13.6360
18 C1b C 24.2793 -12.3346
19 C1a C 25.6685 -12.0754
BOND 19
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 1
11 5 12 1
12 6 13 1
13 6 14 1
14 12 15 2
15 13 16 2
16 8 13 1
17 10 17 3
18 17 18 1
19 18 19 1
|
|---|
