| Entry |
|
|---|
| Name |
Minaprine (USAN/INN);
Cantor (TN) |
|---|
| Formula |
C17H22N4O
|
|---|
| Exact mass |
298.1794
|
|---|
| Mol weight |
298.3828
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase A (MAO-A) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX07 Minaprine
D05039 Minaprine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
DG00954 Minaprine
D05039 Minaprine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00954 Minaprine
D05039 Minaprine
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAOA
D05039 Minaprine (USAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D05039
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
DG00954 Minaprine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00954 Minaprine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8y C 9.2400 -16.8000
2 C8x C 9.2400 -18.2000
3 C8y C 10.4524 -18.9000
4 C8y C 11.6649 -18.2000
5 N5x N 11.6649 -16.8000
6 N5x N 10.4524 -16.1000
7 C8y C 8.0276 -16.1000
8 N1b N 12.8960 -18.9110
9 C1a C 10.4524 -20.2998
10 C8x C 8.0276 -14.7002
11 C8x C 6.8151 -14.0002
12 C8x C 5.6027 -14.7002
13 C8x C 5.6027 -16.1000
14 C8x C 6.8151 -16.8000
15 C1b C 14.1012 -18.2153
16 C1b C 15.2835 -18.8981
17 N1y N 16.4775 -18.2088
18 C1x C 17.6654 -18.8948
19 C1x C 18.8779 -18.1949
20 O2x O 18.8780 -16.7949
21 C1x C 17.6901 -16.1089
22 C1x C 16.4776 -16.8088
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 4 8 1
9 3 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 7 14 1
16 8 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 17 22 1
|
|---|
