| Entry |
|
|---|
| Name |
Nisoxetine (USAN/INN) |
|---|
| Formula |
C17H21NO2
|
|---|
| Exact mass |
271.1572
|
|---|
| Mol weight |
271.3541
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
|
|---|
| Efficacy |
Antidepressant, Selective noradrenaline reuptake inhibitor (NRI) |
|---|
| Comment |
Fluoxetine derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
D05173 Nisoxetine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D05173 Nisoxetine (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C1c C 23.8146 -15.3046
2 C8y C 23.8146 -16.7128
3 O2a O 25.0419 -14.5974
4 C1b C 22.5876 -14.5974
5 C8x C 22.5818 -17.4200
6 C8x C 25.0359 -17.4200
7 C8y C 26.2632 -15.3046
8 C1b C 21.3722 -15.2986
9 C8x C 22.5818 -18.8339
10 C8x C 25.0359 -18.8339
11 C8x C 26.2632 -16.7128
12 C8y C 27.4845 -14.5974
13 N1b N 20.1449 -14.5916
14 C8x C 23.8146 -19.5411
15 C8x C 27.4786 -17.4200
16 C8x C 28.7058 -15.3046
17 C1a C 18.9236 -15.2986
18 C8x C 28.7058 -16.7187
19 O2a O 27.4851 -13.2302
20 C1a C 28.7165 -12.5198
BOND 21
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 4 8 1
8 5 9 2
9 6 10 1
10 7 11 2
11 7 12 1
12 8 13 1
13 9 14 1
14 11 15 1
15 12 16 2
16 13 17 1
17 15 18 2
18 10 14 2
19 16 18 1
20 12 19 1
21 19 20 1
|
|---|
