| Entry |
|
|---|
| Name |
Norgestimate (USP/INN) |
|---|
| Formula |
C23H31NO3
|
|---|
| Exact mass |
369.2304
|
|---|
| Mol weight |
369.4971
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (mixture): | D10590<US> |
|
|---|
| Efficacy |
Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
Component of Prefest (TN)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
D05209 Norgestimate
DG01666 Progesterone receptor agonist
D05209 Norgestimate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D05209 Norgestimate (USP/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 C1y C 27.4218 -18.5468
2 C1z C 27.4278 -17.1810
3 C1y C 26.2398 -19.2328
4 C1x C 29.7858 -18.5529
5 C1z C 28.6098 -16.4950
6 C1x C 26.2335 -16.5012
7 C1b C 27.3788 -15.6682
8 C1y C 25.0638 -18.5591
9 C1x C 26.2523 -20.5924
10 C1x C 29.7920 -17.1872
11 C3b C 29.7552 -15.8214
12 O7a O 28.6038 -14.8185
13 C1x C 25.0512 -17.1932
14 C1y C 23.8941 -19.2390
15 C1x C 25.0761 -21.2661
16 C3a C 30.9005 -15.1416
17 C2y C 23.8941 -20.5862
18 C1x C 22.7304 -18.5774
19 C2x C 22.7304 -21.2661
20 C1x C 21.5729 -19.2390
21 C2y C 21.5729 -20.5862
22 N2b N 20.4153 -21.2478
23 O1b O 19.2429 -20.5641
24 C1a C 26.1334 -15.0022
25 C7a C 28.6038 -13.4176
26 C1a C 29.7850 -12.7359
27 O6a O 27.3856 -12.7138
BOND 30
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 2 7 1 #Up
7 3 8 1
8 3 9 1
9 4 10 1
10 5 11 1 #Down
11 5 12 1 #Up
12 6 13 1
13 8 14 1
14 9 15 1
15 11 16 3
16 14 17 1
17 14 18 1
18 17 19 2
19 18 20 1
20 19 21 1
21 21 22 2
22 5 10 1
23 8 13 1
24 15 17 1
25 20 21 1
26 22 23 1
27 7 24 1
28 12 25 1
29 25 26 1
30 25 27 2
|
|---|
