KEGG   DRUG: Streptozocin
Entry
D05932                      Drug                                   
Name
Streptozocin (JAN/USAN/INN);
Streptozotocin;
Zanosar (TN)
Product
Formula
C8H15N3O7
Exact mass
265.091
Mol weight
265.2206
Structure
Simcomp
Class
Antineoplastic
 DG01677  Alkylating agent
  DG01724  Nitrosourea
Remark
Same as: C07313
Therapeutic category: 4219
ATC code: L01AD04
Product: D05932<JP/US>
Efficacy
Antineoplastic, Alkylating agent
  Disease
Islet cell carcinoma of the pancreas [DS:H00045]
Target
DNA
Interaction
Structure map
map07040  Antineoplastics - alkylating agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AD Nitrosoureas
     L01AD04 Streptozocin
      D05932  Streptozocin (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Alkylating Agents
   Streptozocin
    D05932  Streptozocin (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   421  Alkylating agents
    4219  Others
     D05932  Streptozocin (JAN/USAN/INN)
Drug groups [BR:br08330]
 Antineoplastic
  DG01677  Alkylating agent
   DG01724  Nitrosourea
    D05932  Streptozocin
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05932
Other DBs
CAS: 18883-66-4
PubChem: 47207590
ChEBI: 9288
LigandBox: D05932
NIKKAJI: J2.751K
KCF data

ATOM        18
            1   C1y C    28.9277  -19.7690
            2   C1y C    27.7156  -20.4683
            3   C1y C    28.9277  -18.3703
            4   N1b N    30.1341  -20.4683
            5   C1y C    26.4975  -19.7690
            6   O1a O    27.7156  -21.8670
            7   O2x O    27.7156  -17.6650
            8   O1a O    30.1341  -17.6650
            9   C5a C    31.3405  -19.7631
            10  C1y C    26.4975  -18.3703
            11  O1a O    25.2854  -20.4683
            12  N1c N    32.5527  -20.4508
            13  O5a O    31.3347  -18.3644
            14  C1b C    25.2854  -17.6650
            15  C1a C    33.7649  -19.7573
            16  N2b N    32.5468  -21.8554
            17  O1a O    24.0615  -18.3527
            18  O3a O    31.3405  -22.5450
BOND        18
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Down
            8     4   9 1
            9     5  10 1
            10    5  11 1 #Down
            11    9  12 1
            12    9  13 2
            13   10  14 1 #Up
            14   12  15 1
            15   12  16 1
            16   14  17 1
            17    7  10 1
            18   16  18 2

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