| Entry |
|
|---|
| Name |
Tenofovir (USAN);
Tenofovir hydrate |
|---|
| Abbr |
TFV |
|---|
| Formula |
C9H14N5O4P. H2O
|
|---|
| Exact mass |
305.0889
|
|---|
| Mol weight |
305.2276
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
|
|---|
| Remark |
| Product (DG01223): | D01982<JP/US> D10605<JP/US> |
|
|---|
| Efficacy |
Antiviral, Reverse transcriptase inhibitor |
|---|
| Target |
HBV reverse transcriptase [KO: K21037] HIV-1 reverse transcriptase [KO: K24802] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Other map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG01223 Tenofovir
D06074 Tenofovir
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
DG01223 Tenofovir
D06074 Tenofovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
HBV reverse transcriptase inhibitor
D06074 Tenofovir (USAN)
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG01223 Tenofovir
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
DG01223 Tenofovir
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 N5x N 27.4472 -16.0632
2 C8x C 27.4472 -17.5298
3 N5x N 26.2600 -18.2282
4 C8y C 25.0028 -17.5298
5 C8y C 25.0028 -16.0632
6 C8y C 26.2600 -15.3648
7 N4y N 23.6759 -17.9489
8 C8x C 22.9076 -16.8314
9 N5x N 23.6759 -15.6441
10 N1a N 26.2600 -13.9680
11 C1b C 23.6759 -19.3457
12 C1c C 22.4886 -20.0441
13 O2a O 21.2315 -19.3457
14 C1b C 20.1141 -20.0441
15 P1b P 18.8569 -19.3457
16 C1a C 22.4886 -21.4409
17 O1c O 17.6445 -18.6457
18 O1c O 19.5569 -18.1332
19 O1c O 18.1569 -20.5581
20 O0 O 31.4281 -19.4155
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 5 9 1
11 6 10 1
12 7 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 12 16 1 #Up
18 15 17 1
19 15 18 2
20 15 19 1
|
|---|
