| Entry |
|
|---|
| Name |
Eptifibatide (INN);
Integrilin (TN) |
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| Product |
|
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| Generic |
EPTIFIBATIDE (Accord Healthcare), EPTIFIBATIDE (Amneal Pharmaceuticals LLC), EPTIFIBATIDE (Athenex Pharmaceutical Division), EPTIFIBATIDE (Avenacy), EPTIFIBATIDE (Baxter Healthcare Corporation), EPTIFIBATIDE (Eugia US LLC), EPTIFIBATIDE (Hainan Shuangcheng Pharmaceuticals), EPTIFIBATIDE (Mylan Institutional LLC), EPTIFIBATIDE (Mylan Institutional LLC), EPTIFIBATIDE (Sagent Pharmaceuticals), EPTIFIBATIDE (Slate Run Pharmaceuticals), EPTIFIBATIDE (Slate Run Pharmaceuticals) |
|---|
| Formula |
C35H49N11O9S2
|
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| Exact mass |
831.3156
|
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| Mol weight |
831.9619
|
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| Structure |
|
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01811 Fibrinogen receptor antagonist
|
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| Remark |
|
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| Efficacy |
Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist |
|---|
| Comment |
Treatment of Acute coronary syndrome
|
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| Target |
|
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| Pathway |
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| Interaction |
|
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| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC16 Eptifibatide
D06888 Eptifibatide (INN) <US>
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
D06888 Eptifibatide
DG01811 Fibrinogen receptor antagonist
D06888 Eptifibatide
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Cell adhesion molecules: other families
Integrins
ITGA2B/ITGB3
D06888 Eptifibatide (INN) <US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D06888
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| Other DBs |
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| KCF data |
ATOM 57
1 C1b C 18.7088 -13.7108
2 C5a C 19.8059 -12.8468
3 N1b N 21.1717 -13.1584
4 C1c C 21.7738 -14.4120
5 C1b C 18.7088 -15.1203
6 C5a C 21.1726 -15.6797
7 N1b N 19.8059 -15.9914
8 C1b C 17.4960 -13.0106
9 S3a S 16.2830 -13.7108
10 N1b N 16.2830 -15.1203
11 C5a C 17.4960 -15.8206
12 S3a S 15.0702 -13.0106
13 C1b C 13.8574 -13.7108
14 C5a C 13.8574 -15.1203
15 C1c C 15.0702 -15.8206
16 C1c C 12.6445 -13.0106
17 N1b N 11.4317 -13.7108
18 C1c C 11.4317 -15.1203
19 N1b N 12.6445 -15.8206
20 C5a C 10.2188 -13.0106
21 C1y C 9.0059 -13.7108
22 N1y N 9.0059 -15.1203
23 C5a C 10.2188 -15.8206
24 C1x C 7.6655 -13.2753
25 C1x C 6.8370 -14.4156
26 C1x C 7.6655 -15.5559
27 O5a O 19.4918 -11.4542
28 O5a O 22.0432 -16.7652
29 O5a O 17.4959 -17.2273
30 O5a O 13.8573 -16.5271
31 O5a O 10.2187 -17.2274
32 O5a O 10.2188 -11.6254
33 C5a C 12.6449 -11.6258
34 C1b C 11.4318 -16.5270
35 O5a O 13.8817 -10.9118
36 N1a N 11.4561 -10.9388
37 C1b C 15.0703 -17.2273
38 C6a C 16.1138 -18.1470
39 O6a O 17.5084 -18.1449
40 O6a O 15.6221 -19.4512
41 C8y C 12.5155 -17.3949
42 C8y C 12.0831 -18.6924
43 C8y C 13.1918 -19.5005
44 N4x N 14.3028 -18.6958
45 C8x C 13.8809 -17.3903
46 C8x C 10.7241 -19.4142
47 C8x C 10.7347 -20.8147
48 C8x C 11.9280 -21.4916
49 C8x C 13.1355 -20.7822
50 C1b C 23.0144 -13.7651
51 C1b C 24.2287 -14.5371
52 C1b C 25.4597 -13.8950
53 C1b C 26.6501 -14.6525
54 N1b N 27.9233 -13.9887
55 C2c C 29.1261 -14.7540
56 N1a N 30.3635 -14.1090
57 N2a N 29.1348 -16.1754
BOND 60
1 3 4 1
2 4 6 1
3 2 3 1
4 5 7 1
5 1 2 1
6 6 7 1
7 1 8 1
8 8 9 1
9 10 11 1
10 5 11 1
11 9 12 1
12 12 13 1
13 14 15 1
14 10 15 1
15 13 16 1
16 16 17 1
17 18 19 1
18 14 19 1
19 17 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 18 23 1
24 21 24 1
25 24 25 1
26 25 26 1
27 22 26 1
28 2 27 2
29 6 28 2
30 11 29 2
31 14 30 2
32 23 31 2
33 20 32 2
34 16 33 1
35 18 34 1
36 33 35 2
37 33 36 1
38 15 37 1
39 37 38 1
40 38 39 2
41 38 40 1
42 34 41 1
43 41 42 1
44 42 43 1
45 43 44 1
46 44 45 1
47 41 45 2
48 42 46 2
49 46 47 1
50 47 48 2
51 48 49 1
52 43 49 2
53 4 50 1
54 50 51 1
55 51 52 1
56 52 53 1
57 53 54 1
58 54 55 1
59 55 56 1
60 55 57 2
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