| Entry |
|
|---|
| Name |
Alclometasone (INN) |
|---|
| Formula |
C22H29ClO5
|
|---|
| Exact mass |
408.1704
|
|---|
| Mol weight |
408.9157
|
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| Structure |
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| Simcomp |
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| Class |
|
|---|
| Remark |
| Product (DG00415): | D01820<JP/US> |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB10 Alclometasone
D07116 Alclometasone (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA10 Alclometasone
D07116 Alclometasone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00415 Alclometasone
D07116 Alclometasone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D07116 Alclometasone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00415 Alclometasone
|
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| Other DBs |
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| KCF data |
ATOM 28
1 C2x C 22.7026 -20.4659
2 C5x C 22.7026 -21.8362
3 C2x C 23.8893 -22.5214
4 C2y C 25.0761 -21.8362
5 C1z C 25.0761 -20.4659
6 C2x C 23.8893 -19.7807
7 C1x C 26.2629 -22.5214
8 C1y C 27.4496 -21.8362
9 C1y C 27.4496 -20.4659
10 C1y C 26.2629 -19.7807
11 C1y C 28.6363 -19.7807
12 C1z C 28.6364 -18.4103
13 C1x C 27.4497 -17.7251
14 C1y C 26.2629 -18.4103
15 C1x C 31.0099 -19.7809
16 C1y C 31.0100 -18.4105
17 C1z C 29.8233 -17.7252
18 C1a C 28.6364 -17.0400
19 C1a C 25.0761 -19.0955
20 O1a O 25.0781 -17.7263
21 X Cl 28.6219 -22.5131
22 C1a C 32.3214 -17.9381
23 O1a O 31.0100 -17.0401
24 C5a C 29.8233 -16.1449
25 O5x O 21.5158 -22.5214
26 O5a O 31.0224 -15.6628
27 C1b C 28.6728 -15.3676
28 O1a O 27.4239 -15.9759
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 12 18 1 #Up
22 5 19 1 #Up
23 14 20 1 #Up
24 8 21 1 #Down
25 16 22 1 #Down
26 17 23 1 #Down
27 17 24 1 #Up
28 2 25 2
29 24 26 2
30 24 27 1
31 27 28 1
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